ArticleGenome biology2026
Geometry-aware graph attention networks to explain single-cell chromatin states and gene expression with SEAGALL.
Article in Genome biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
Abstract
High-throughput single-cell sequencing is widely used to study cell identity. We present SEAGALL (Single-cell Explainable Geometry-Aware Graph Attention Learning pipeLine), a deep learning method to quantify the impact of molecular features on cellular phenotype, based on geometry-regularised autoencoders (GRAE) and explainable graph attention networks (X-GAT). The GRAE embeds the data into a latent space to build a reliable cell-cell graph. The GAT is trained to learn the annotations and XAI is used to explain the predictions, unravelling the features driving cell identity. SEAGALL extracts specific and stable signatures from multiple omics experiments, going beyond differential marker genes.
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Registered trials
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