Evidence map›Paper›PMID 42026606›Full record

ArticleBMC musculoskeletal disorders2026

A finite element analysis of the biomechanical stability of tri-cortical versus traditional pedicle screw fixation in adult thoracic spine.

Kai Sun, Ziyang Tang, Jie Li, Xiaodong Qin, Saihu Mao, Benlong Shi, Yong Qiu, Zezhang Zhu, Zhen Liu

Abstract readComparative Study
In one paragraph

Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Authors and funding

9 authors.

Kai Sun *Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Ziyang Tang *Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Jie LiDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Xiaodong QinDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Saihu MaoDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Benlong ShiDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Yong QiuDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Zezhang ZhuDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China.
Zhen LiuDivision of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School, Nanjing University, Zhongshan Road 321, Nanjing, 210008, China. drliuzhen@163.com.

Funding

1. The National Natural Science Foundation of China (NSFC) 822725452. Fundings for Clinical Trials from the Affiliated Drum Tower Hospital, Medical School of Nanjing University 2022-LCYJ-MS-22
6 · The paper itself

Abstract

backgroundTo assess the biomechanical stability of tri-cortical pedicle screw fixation in adult thoracic vertebra using finite element analysis and to compare its performance with traditional fixation methods.

methodsA three-dimensional finite element model of T5-11 thoracic vertebrae was established based on CT data from a healthy adult volunteer. Four different fixation groups were designed: Group A (Short-segment pedicle screw fixation from T7 to T10), Group B (Long-segment pedicle screw fixation from T6 to T10), Group C (Short-segment pedicle screw fixation with a tri-cortical pedicle screw at T7), and Group D (Short-segment pedicle screw fixation with two tri-cortical pedicle screws at T7 and T8). Biomechanical analysis was performed under six physiological loading conditions (flexion, extension, left/right rotation, left/right lateral bending) with 8 Nm moment and 400 N axial preload.

resultsGroups C and D with tri-cortical pedicle screw fixation demonstrated numerically lower displacement compared to traditional fixation groups (A and B) under all loading conditions. The displacement in Group C decreased by 11.11%-31.47% and in Group D by 12.96%-32.34% compared to Group A across all loading conditions. Group D showed slightly better performance than Group C in displacement. Stress analysis revealed substantial reductions in adjacent segment stress (annulus fibrosus, nucleus pulposus, and cartilage endplate) in tri-cortical groups, with decreases ranging from 59.25% to 95.46% compared to Group A. Minimal difference was observed in internal fixation stress between groups.

conclusionTri-cortical pedicle screw fixation provides superior biomechanical stability in thoracic vertebra compared to traditional fixation methods, with numerically lower adjacent segment stress, suggesting potential benefits for reducing the biomechanical risk factors of proximal junctional kyphosis in clinical applications. This study provides biomechanical evidence supporting the use of tri-cortical pedicle screw fixation as a novel strategy for reducing the risk of proximal junctional kyphosis in adult spinal deformity surgery.

Indexed as

Finite Element AnalysisPedicle ScrewsSpinal FusionThoracic VertebraeAdultBiomechanical PhenomenaHumansMaleTomography, X-Ray ComputedAdult spinal deformityAdult thoracic vertebraBiomechanical stabilityFinite element analysisProximal junctional kyphosisTri-cortical pedicle screw

Identifiers

PMID42026606
PMCPMC13238054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.