Evidence map›Paper›PMID 42026496›Full record

ArticleBMC neurology2026

Diffuse sulcal hyperintensity on MRI as a radiological correlate of transient neurological deficits in chronic subdural hematoma.

Shota Yoshimura, Susumu Yamaguchi, Hikaru Nakamura, Kosuke Hirayama, Yukishige Hayashi, Takayuki Matsuo

Abstract read
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Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Shota YoshimuraDepartment of Neurosurgery, Nagasaki Prefecture Shimabara Hospital, 7895, Shimokawajiri-machi, Shimabara, 855-0861, Japan. gm.yy.shota@gmail.com.
Susumu YamaguchiDepartment of Neurosurgery, Nagasaki Harbor Medical Center, 6-39, Shinchi- machi, Nagasaki, 850-8555, Japan.
Hikaru NakamuraDepartment of Neurosurgery, Nagasaki Prefecture Shimabara Hospital, 7895, Shimokawajiri-machi, Shimabara, 855-0861, Japan.
Kosuke HirayamaDepartment of Neurosurgery, Nagasaki Prefecture Shimabara Hospital, 7895, Shimokawajiri-machi, Shimabara, 855-0861, Japan.
Yukishige HayashiDepartment of Neurosurgery, Nagasaki Prefecture Shimabara Hospital, 7895, Shimokawajiri-machi, Shimabara, 855-0861, Japan.
Takayuki MatsuoDepartment of Neurosurgery, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransient neurological deficits (TND) may present as the initial symptom of chronic subdural hematoma (CSDH). Although a relationship between sulcal hyperintensity (SHI) on FLAIR images and TND has been suggested, existing evidence is limited to case reports and small-scale cohort studies. This study aimed to investigate the association between diffuse SHI and TND in patients with CSDH.

methodsThis single-center retrospective study included 127 patients with CSDH who underwent perioperative CT and MRI including FLAIR sequences, between January 2017 and March 2025. To identify factors associated with TND, univariate and multivariable logistic regression analyses were used to estimate odds ratios (ORs) with 95% confidence intervals (CIs). SHI on FLAIR was defined as marked hyperintensity along cerebral sulci adjacent to the hematoma, categorized as diffuse or focal.

resultsAmong the 127 patients (median age, 82 [74–86] years, 86 male) with CSDH, 22 (median age, 81 [72–85] years, 17 male) presented with diffuse SHI. Of the 22 patients with diffuse SHI, nine (40.91%) underwent TND. The presence of diffuse SHI was independently associated with TND (adjusted OR; 17.07, 95% CI; 4.71–73.23, p < 0.01).

conclusionsThis study demonstrates a significant correlation between preoperative TND and diffuse SHI in patients with CSDH. These findings may serve as a potential biomarker for TND in patients with CSDH, providing useful information that can complement existing diagnostic methods.

Indexed as

Hematoma, Subdural, ChronicMagnetic Resonance ImagingNervous System DiseasesAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesTomography, X-Ray Computedchronic subdural hematomafluid attenuated inversion recoverymagnetic resonance imagingsulcal hyperintensitytransient neurological deficits

Identifiers

PMID42026496
PMCPMC13237949

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.