Evidence map›Paper›PMID 42026342›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026

Difference in clinical characteristics between functional syncope and vasovagal syncope in children.

Zifeng Huang, Yi Xu, Shuo Wang, Ping Liu, Xingfang Zeng, Liping Liu, Hong Cai, Yuwen Wang, Liqun Liu, Runmei Zou and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zifeng HuangDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Yi XuDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Shuo WangDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Ping LiuDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Xingfang ZengDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Liping LiuDepartment of Pediatric Cardiology, Children's Medical Center, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, 410005, China.
Hong CaiDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Yuwen WangDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Liqun LiuDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Runmei ZouDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Cheng WangDepartment of Pediatric Cardiovasology, The Second Xiangya Hospital, Children's Medical Center, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China. wangcheng2nd@csu.edu.cn.ORCID http://orcid.org/0000-0002-7120-0654

Funding

Department of Science and Technology of Hunan Province 2023SK4018Department of Science and Technology of Hunan Province 2025ZK4179Natural Science Foundation of Hunan Province 2021JJ70093Natural Science Foundation of Hunan Province 2023JJ30812Natural Science Foundation of Hunan Province 2025JJ81175
6 · The paper itself

Abstract

backgroundFunctional syncope and vasovagal syncope (VVS) in children both present with transient loss of consciousness (TLOC) and are clinically challenging to differentiate. This study aims to delineate the distinguishing features among factors associated with TLOC induction in these two conditions.

methodsA total of 31 children presenting with syncope and diagnosed as functional syncope were enrolled in the functional syncope group; concurrently, 40 children presenting with syncope and diagnosed with VVS were enrolled in the VVS group. Clinical manifestations— including demographic characteristics, precipitating factors, prodromal symptoms, syncope episode characteristics, family history, and psychosocial stressors—were systematically compared between the two groups.

resultsBody weight was significantly higher in the functional syncope group than in the VVS group (P < 0.05). No statistically significant differences were observed between the groups in terms of sex distribution, age, body height, or baseline resting heart rate (P > 0.05). Compared with the VVS group, the functional syncope group exhibited significantly fewer identifiable triggers, fewer presyncope symptoms, and a lower prevalence of familial syncope history (all P < 0.05). Conversely, the functional syncope group demonstrated significantly longer syncope duration, higher syncope frequency, and greater exposure to emotional stress events (all P < 0.05). Disease duration did not differ significantly between the two groups (P > 0.05).

conclusionsChildren with functional syncope exhibit distinct clinical profiles relative to those with VVS, characterized by fewer precipitating factors and prodromal symptoms, longer duration and higher frequency of syncope episodes, reduced familial syncope history, and increased association with emotional stress events.

Indexed as

SyncopeSyncope, VasovagalAdolescentChildChild, PreschoolFemaleHumansMaleChildrenClinical manifestationsFunctional syncopeVasovagal syncope

Identifiers

PMID42026342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.