Evidence map›Paper›PMID 42026321›Full record

ArticleArchives of orthopaedic and trauma surgery2026

20 years of blood management and VTE prevention in orthopedic surgery in the Netherlands - a nationwide survey.

Ruben Y Kok, Joost-Jelle T M Gerritsen, Cees C P M Verheyen, Banne Németh, Harmen B Ettema

Abstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruben Y Kok *Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands.
Joost-Jelle T M Gerritsen *Department of Orthopedics, Isala, Zwolle, Netherlands.
Cees C P M VerheyenDepartment of Orthopedics, Isala, Zwolle, Netherlands.
Banne NémethDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands. B.Nemeth@lumc.nl.
Harmen B EttemaDepartment of Orthopedics, Isala, Zwolle, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdvances in arthroplasty care have progressively improved patient outcomes, including reduced bleeding and venous thromboembolism rates. Consequently, blood-saving measures applied pre-, peri- and postoperatively as well as thromboprophylaxis regimens have evolved over time. To evaluate these developments, we conducted a 2023 follow-up to the national surveys from 2002, 2007 and 2012, examining current blood-saving strategies and thromboprophylaxis use in The Netherlands. MATERIALS AND

methodsIn 2023, a questionnaire designed to match the previous surveys was distributed to all orthopedic departments in the Netherlands. The collected data were summarized and compared with previous findings.

resultsResponses were received from 61% of the Dutch orthopedic departments. Blood-saving practices have shifted significantly toward the use of tranexamic acid, accompanied by a decline in other measures. In particular, the use of drains, blood transfusions, and erythropoietin supplementation has decreased substantially. Thromboprophylaxis protocols showed fewer changes, although the average duration of prophylaxis has shortened, with low-molecular-weight heparin remaining the most commonly used anticoagulant.

conclusionsAdvances in surgical techniques and postoperative care around arthroplasty appear to have reduced concerns about perioperative blood loss to a level where the use of tranexamic acid alone is considered sufficient to control blood loss, rendering many previously popular perioperative blood-saving measures redundant. In contrast, despite a decline in thrombotic complications associated with the introduction of fast-track surgery, thromboprophylaxis protocols have remained largely unchanged. These findings highlight the opportunity to further balance the risks of bleeding and thrombosis following arthroplasty.

Indexed as

Blood Loss, SurgicalOrthopedic ProceduresVenous ThromboembolismAnticoagulantsBlood TransfusionHeparin, Low-Molecular-WeightHumansNetherlandsSurveys and QuestionnairesTranexamic AcidAnticoagulantsHeparin, Low-Molecular-WeightTranexamic AcidBleedingHip arthroplastyKnee arthroplastyThromboprophylaxisVenous thromboembolism

Identifiers

PMID42026321
PMCPMC13106243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.