Evidence map›Paper›PMID 42026303›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Challenging barriers in OSA: Outcomes of "Down under" pharyngoplasty and coblation tongue channelling.

Michael V Nasserallah, Mylestone Monna, Zanda Edwards, Mark Lum, Vicky Tobin, Vibhuti R Mahanta, Diamanti Diamantaras, Subhaschandra Shetty, Juan Mulder, Nalaka de Silva

Abstract readMulticenter Study
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Michael V NasserallahDepartment of ENT Surgery, Frankston Hospital, Peninsula Health, Frankston, Australia. Michael.nasserallah@gmail.com.ORCID http://orcid.org/0000-0003-3618-2785
Mylestone MonnaDepartment of ENT Surgery, Frankston Hospital, Peninsula Health, Frankston, Australia.
Zanda EdwardsDepartment of ENT Surgery, Frankston Hospital, Peninsula Health, Frankston, Australia.
Mark LumDepartment of ENT Surgery, Frankston Hospital, Peninsula Health, Frankston, Australia.
Vicky TobinDepartment of Surgery, Frankston Hospital, Peninsula Health, Frankston, Australia.
Vibhuti R MahantaDepartment of ENT Surgery, Frankston Hospital, Peninsula Health, Frankston, Australia.
Diamanti DiamantarasDepartment of ENT Surgery, Frankston Hospital, Peninsula Health, Frankston, Australia.
Subhaschandra ShettyWhangārei Hospital, Whangārei, New Zealand.
Juan MulderDepartment of Respiratory Medicine, Peninsula Health, Frankston, Australia.
Nalaka de SilvaDepartment of ENT Surgery, Frankston Hospital, Peninsula Health, Frankston, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObstructive sleep apnoea (OSA) is a growing health concern with significant personal and public health costs. This is the first study to evaluate the efficacy of “Down Under” barbed reposition pharyngoplasty (DU-BRP) and coblation tongue channelling (CCT) in adults with OSA, particularly those with unfavourable anatomical phenotypes.

methodsA prospective, two-centre cohort trial was conducted with 105 patients undergoing DU-BRP and CCT. Outcomes included Apnoea-Hypopnoea Index (AHI), Oxygen Desaturation Index (ODI4%), Epworth Sleepiness Scale (ESS), and changes in upper airway anatomy, measured pre- and 3–6 months post-operatively.

resultsOf the 105 patients, 92 attended all postoperative appointments and 75 completed postoperative polysomnography and were included in the objective outcome analysis. The cohort (68/92 male, mean age 40.6 ± 12.7 years) showed significant improvement across all measures. Median (IQR) AHI decreased from 27 (33.4) to 7.1 (11.6) events/hr (p < 0.001), ESS from 12.5 (8) to 4 (4) points (p < 0.001), and ODI4% from 25.4 (37) to 7 (17) (p < 0.001). Surgical success (AHI < 20 with > 50% reduction) was achieved in 75% of patients, with 43% considered complete responders (AHI < 5). Among patients with challenging anatomy, success rates were 76% for those with Friedman stage 3 anatomy, 62.5% for those with complete circumferential velum collapse, and 73% for those with complete base of tongue collapse.

conclusionDU-BRP combined with CCT was associated with significant improvements in objective and patient-reported OSA outcomes at six months, including in patients with unfavourable anatomical phenotypes. Future research should refine staging systems incorporating physiologic phenotypes to enhance the predictability of outcomes of these surgical techniques.

Indexed as

PharynxSleep Apnea, ObstructiveTongueAdultFemaleHumansMaleMiddle AgedPolysomnographyProspective StudiesTreatment OutcomeBarbed reposition pharyngoplastyCoblation tongue channellingMultilevel airway surgeryObstructive sleep apnoeaUpper airway surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.