Evidence map›Paper›PMID 42026233›Full record

ArticleTechniques in coloproctology2026

Milligan-Morgan hemorrhoidectomy, mucopexy, and hybrid combination for grade III hemorrhoids: a large retrospective cohort study.

Gaetano Gallo, Veronica De Simone, Gianpiero Gravante, Salvatore Sorrenti, Simone Tierno, Federico Tomassini, Antonio Crucitti, Pierpaolo Sileri, Marco La Torre

Abstract readComparative Study
In one paragraph

Article in Techniques in coloproctology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Gaetano GalloColorectal Surgery Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.
Veronica De SimoneColorectal Surgery Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.
Gianpiero GravanteDepartment of General Surgery, Azienda Sanitaria Locale ASL Lecce, Ospedale "Francesco Ferrari", Viale Francesco Ferrari 1, 73042, Casarano, Italy. ggravante@hotmail.com.
Salvatore SorrentiDepartment of Surgery, Sapienza University of Rome, Rome, Italy. salvatore.sorrenti@uniroma1.it.
Simone TiernoDepartment of Surgery, Ospedale Vannini, Rome, Italy.
Federico TomassiniDepartment of Surgery, Ospedale Grassi di Ostia, Rome, Italy.
Antonio CrucittiDepartment of Surgery, Ospedale Cristo Re, Rome, Italy.
Pierpaolo SileriColorectal Surgery Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.
Marco La TorreDepartment of Surgery, Ospedale Cristo Re, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMucopexy has emerged as a nonexcisional alternative to Milligan-Morgan (MM) hemorrhoidectomy.

objectiveThis study compares MM, mucopexy, and hybrid MM/mucopexy procedures in patients with grade III hemorrhoidal disease (HD).

designRetrospective cohort study.

settingTertiary referral setting. PATIENTS: Symptomatic grade III HD treated between 2016 and 2018.

interventionsFour groups were defined: group 1 included patients treated with MM alone; group 2 received mucopexy on one pile combined with MM on the remaining two; group 3 underwent mucopexy on two piles with MM on the remaining one; and group 4 was treated with mucopexy alone. MAIN OUTCOMES MEASURES: Recurrence rates and patient-reported outcome measures (PROMs) using a visual-analogic scale (VAS) at 2 years, postoperative pain at 7 days, early complication rates at 30 days, and PROMs at 30 days.

resultsA total of 686 consecutive patients with III-degree HD were included in the analysis. The most frequent approach was MM alone (group 1, n = 309, 45%), followed by mucopexy alone (group 4, n = 138, 20.2%), then the combined approaches (group 2, n = 120, 17.5%; group 3, n = 119, 17.3%). Group 4 had the lowest pain scores and the highest 30-day PROM (p < 0.001), whereas group 1 showed the best long-term results, with the lowest recurrence rate (4.2% versus 14.5% in group 4) and highest long-term PROM. LIMITATIONS: Retrospective analysis.

conclusionsMucopexy and the hybrid procedures reduce morbidity and enhances early postoperative PROM in grade III HD. However, its higher recurrence rate suggests that a patient- and pile-specific approach may help balance efficacy with surgical invasiveness.

Indexed as

HemorrhoidectomyHemorrhoidsAdultAgedFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresPostoperative ComplicationsPostoperative PainRecurrenceRetrospective StudiesSeverity of Illness IndexTreatment Outcomecombined approachIII degree Hemorrhoidal DiseaseMilligan-Morgan hemorrhoidectomyMucopexySurgicalApproach

Identifiers

PMID42026233
PMCPMC13269399

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