ArticlePediatric research2026
Neurodevelopment after a strength-based intervention in children born extremely preterm: a randomised controlled trial.
Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Neonatal brain-age models in full- and preterm infants.Developmental cognitive neuroscience · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtremely preterm birth increases the risk of neurodevelopmental impairments. Early interventions supporting child and parent may improve child neurodevelopment, but evidence is limited. We aimed to evaluate the effect of the Stockholm Preterm Interaction-Based Intervention on neurodevelopmental outcomes at 24 months' corrected age. Risk of autism spectrum disorder was examined as separate outcome. We also investigated whether the effect varied according to biological and psychosocial factors including maternal depressive symptoms.
methodsThis randomised controlled trial included 130 infants born extremely preterm. Participants were randomised to receive either the intervention in addition to an extended follow-up program (intervention group) or solely the extended follow-up program (control group). Neurodevelopment was assessed at 24 months' corrected age using the Bayley Scales of Infant and Toddler Development 3
resultsNo significant group differences were found in cognitive, language, or motor development, neither in the overall group nor within the sub-group of children at risk of autism spectrum disorder. No interaction effects by biological and psychosocial factors were observed.
conclusionNeurodevelopmental effects of the intervention were not observed at 24 months' corrected age in our cohort of children born extremely preterm. Follow-up is important to evaluate long-term effects. IMPACT STATEMENT: A strength-based, post-discharge parent-infant intervention showed no short-term effects on neurodevelopment at 24 months' corrected age in children born extremely preterm. This trial contributes to the limited evidence on early, family-centered interventions after extremely preterm birth, indicating that measurable benefits may require longer follow-up or higher intervention intensity. Our findings emphasize the importance of continued longitudinal evaluation and refinement of early support programs to better promote both child development and parental well-being. Around 44% of the children scored below -1 SD indicating risk in cognitive, language or motor development, highlighting the need for interventions and continuous follow-up.
Identifiers
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Registered trials
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