ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026
Congenital internal carotid artery agenesis in an infant presenting with stroke: importance of carotid canal assessment.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Congenital agenesis of the internal carotid artery (ICA) is a uncommon developmental anomaly that may remain clinically silent due to collateral circulation. In infants, however, inadequate collateralization can predispose to ischemic events particularly during systemic illness. We report an 11-month-old female who presented with acute-onset right sided hemiparesis in the setting of sepsis. CT angiography demonstrated complete absence of the left ICA with preservation of the external carotid artery. Axial skull base CT in bone window revealed absence of the left carotid canal, confirming congenital ICA agenesis and excluding acquired arterial occlusion. Collateral intracranial supply was provided via the vertebro-basilar circulation and ophthalmic artery branches. This case highlights the critical role of skull base imaging in differentiating congenital ICA agenesis from thrombosis or dissection in infants presenting with stroke and underscored an important diagnostic pitfall in pediatric neurovascular imaging.
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