Evidence map›Paper›PMID 42026166›Full record

ArticleCardiovascular and interventional radiology2026

Transarterial Embolization for the Treatment of Symptomatic Hip Osteoarthritis.

Florian Nima Fleckenstein, Tazio Maleitzke, Stephan Oehme, Stefanie Donner, Timo Alexander Auer, Alexander Hildebrandt, Carsten Perka, Jens Vogel-Claussen, Bernhard Gebauer, Tobias Winkler and 1 more

Abstract read
In one paragraph

Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Florian Nima FleckensteinDepartment of Diagnostic and Interventional Radiology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Charité Campus Mitte (CCM), Charitéplatz 1, 10117, Berlin, Germany. florian.fleckenstein@charite.de.ORCID http://orcid.org/0000-0003-1088-1721
Tazio MaleitzkeCenter for Musculoskeletal Surgery, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Stephan OehmeBerlin Institute of Health (BIH), Charité - Universitätsmedizin Berlin, Anna-Louisa-Karsch 2, 10178, Berlin, Germany.
Stefanie DonnerCenter for Musculoskeletal Surgery, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Timo Alexander AuerDepartment of Diagnostic and Interventional Radiology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Charité Campus Mitte (CCM), Charitéplatz 1, 10117, Berlin, Germany.
Alexander HildebrandtBerlin Institute of Health (BIH), Charité - Universitätsmedizin Berlin, Anna-Louisa-Karsch 2, 10178, Berlin, Germany.
Carsten PerkaCenter for Musculoskeletal Surgery, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Jens Vogel-ClaussenDepartment of Diagnostic and Interventional Radiology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Charité Campus Mitte (CCM), Charitéplatz 1, 10117, Berlin, Germany.
Bernhard GebauerDepartment of Diagnostic and Interventional Radiology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Charité Campus Mitte (CCM), Charitéplatz 1, 10117, Berlin, Germany.
Tobias WinklerCenter for Musculoskeletal Surgery, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Federico CollettiniDepartment of Diagnostic and Interventional Radiology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Charité Campus Mitte (CCM), Charitéplatz 1, 10117, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the safety and clinical effectiveness of transarterial embolization (TAE) using temporary embolic agents in patients with symptomatic hip osteoarthritis (OA) refractory to conservative treatment. MATERIALS AND

methodsThis single-centre retrospective analysis included patients undergoing TAE between January 2023 and April 2025. Eligibility required ≥ 3 months of clinically and radiographically confirmed hip OA unresponsive to conservative therapy. Embolization was performed using rapidly resorbable gelatin microspheres or imipenem/cilastatin. Outcomes included technical success, adverse events, and patient-reported outcomes (numeric rating scale [NRS] pain; Hip Disability and Osteoarthritis Outcome Score [HOOS]) assessed at baseline and up to 12 months. Clinically meaningful improvement was defined using minimum clinically important difference (MCID) thresholds (≥ 2 points for NRS; ≥ 10 points for HOOS).

resultsForty-one patients (median age 65 years) underwent TAE with a technical success rate of 97.5% (40/41). The lateral circumflex femoral artery was embolized in all cases, with additional internal iliac branches treated in 27.5% (11/40). No major or moderate adverse events occurred; minor transient skin discoloration was observed in 7.3% (all after imipenem/cilastatin). Median NRS decreased from 7 to 4 at 12 months (p < .001), with significant improvement across all HOOS domains. MCID was achieved in 64.3% for NRS and 85-92% for HOOS. Two patients (4.9%) underwent total hip replacement.

conclusionTAE using temporary embolic agents was associated with sustained pain reduction and functional improvement at 12 months with a favourable safety profile.

Indexed as

Embolization, TherapeuticOsteoarthritis, HipAgedCilastatin, Imipenem Drug CombinationFemaleGelatinHumansMaleMicrospheresMiddle AgedPain MeasurementRetrospective StudiesTreatment OutcomeCilastatin, Imipenem Drug CombinationGelatin

Identifiers

PMID42026166
PMCPMC13337951

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.