SynthesisScientific reports2026
Association of the CD14 gene rs2569190 polymorphism with the risk of allergic rhinitis: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Allergic rhinitis (AR) is a type I hypersensitivity disease of the nasal mucosa that is mediated by immunoglobulin E (IgE). The relationship between the rs2569190 polymorphism of the CD14 gene and the risk of AR remains unclear. Therefore, we performed a meta-analysis to evaluate this relationship. We performed a systematic search and found 8 relevant publications that were included in this meta-analysis, consisting of 1,022 cases and 1,045 controls. Statistical analyses were conducted via the "meta" package in R studio. The odds ratios (ORs) with corresponding 95% confidence intervals (CIs) were calculated. No association was found between CD14 rs2569190 and AR risk in the total study population. However, subgroup analysis revealed that the rs2569190 T allele was most likely associated with an increased risk of AR in the Egyptian subgroup [allelic model (T vs. C): OR = 2.56, 95% CI = 1.49-4.43, I
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