Observational studyThe Journal of pediatrics2026
Characterizing Barriers to Living Donor Liver Transplantation for Pediatric Recipients: Qualitative Results from the SOCIAL-Tx Study.
Observational study in The Journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04551742 (Social & Contextual Impact on Children Undergoing Liver Transplantation), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Social & Contextual Impact on Children Undergoing Liver Transplantation
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Authors and funding
12 authors.
Funding
Abstract
objectiveTo characterize barriers and facilitators influencing caregiver decision-making regarding living donor liver transplantation (LDLT) for children with end-stage liver disease. STUDY
designThis qualitative study used semistructured, in-depth interviews conducted between May 2023 and March 2025 with caregivers of pediatric liver transplant recipients enrolled in the Social & Contextual Impact on Children Undergoing Liver Transplantation study cohort. Interviews were recorded and professionally transcribed, then independently coded by 3 reviewers using a codebook informed by the capability, opportunity, motivation - behavior model, an implementation science framework. Codes were compared and reconciled to generate themes.
resultsEighteen caregivers participated; 50% reported household incomes <150% of the federal poverty level. Seven themes emerged: (1) insufficient time to comprehend transplant options, (2) perceived or actual lack of eligible donors in caregiver's social network, (3) concern about donor health consequences, (4) challenge of being both a caregiver and donor, (5) discordance between discomfort asking others to donate and response received, (6) limited knowledge about differences between whole and split liver, and (7) the appeal of flexible surgical scheduling offered by LDLT. These themes highlight the interplay between cognitive, social, and practical factors influencing pursuit of living donation.
conclusionsStrategies to support decision-making about LDLT should include counseling about the procedure's benefits early in the transplant evaluation process, helping identify nondirected donors and reducing the caregiving burden during the donor recovery period. Such efforts should prioritize under-resourced families to enhance equitable outcomes for children with end-stage liver disease. CLINICAL
trial registrationwww. CLINICALTRIALS: gov NCT04551742.
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