Evidence map›Paper›PMID 42025611›Full record

Trial reportPsychiatry research2026

Compensatory cognitive training for unstably housed, post-9/11 veterans in residential mental health treatment: A randomized controlled trial.

Elizabeth W Twamley, Amber V Keller, Jacqueline E Maye, Tara A Austin, Jessica J Zakrzewski, Laura M Campbell, Ilyssa H Silverman, Delaney Pickell, Jillian M R Clark, Michelle Z Schy and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychiatry research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elizabeth W TwamleyCenter of Excellence for Stress and Mental Health and Research Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA 92161, USA; Department of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA. Electronic address: etwamley@health.ucsd.edu.
Amber V KellerSDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA.
Jacqueline E MayeDepartment of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA; Center of Excellence for Stress and Mental Health and Psychology Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA 92161, USA.
Tara A AustinCenter of Excellence for Stress and Mental Health and Research Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA 92161, USA; Department of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA.
Jessica J ZakrzewskiDepartment of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA.
Laura M CampbellDepartment of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA.
Ilyssa H SilvermanSDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA.
Delaney PickellCenter of Excellence for Stress and Mental Health and Research Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA 92161, USA; Department of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA.
Jillian M R ClarkDepartment of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA; Center of Excellence for Stress and Mental Health and Psychology Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA 92161, USA.
Michelle Z SchyCenter of Excellence for Stress and Mental Health and Research Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA 92161, USA; Department of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA.
Mili ParikhCenter of Excellence for Stress and Mental Health and Research Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA 92161, USA; Department of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA.
Amy J JakDepartment of Psychiatry, UC San Diego, 9500 Gilman Drive (MC 9116A), La Jolla, CA 92093, USA; Center of Excellence for Stress and Mental Health and Psychology Service, VA San Diego Healthcare System, 3350 La Jolla Village Drive (116A), San Diego, CA 92161, USA.

Funding

FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
Fellowship on Biological Psychiatry and NeuroscienceT32MH018399 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pei-an (Betty) Shih · 1986 to 2026
$7.3M
NIMH NIH HHS T32 MH018399NIMH NIH HHS T32 MH019934RRD VA I01 RX001972RRD VA IK2 RX003821RRD VA IK2 RX004764RRD VA IK6 RX003504
6 · The paper itself

Abstract

Addressing homelessness in returning Veterans is a national priority. Contributors to homelessness include traumatic brain injury (TBI), psychiatric illness, substance abuse, and other medical conditions that are associated with cognitive impairment, which can interfere with obtaining income, housing, and rehabilitation. Compensatory Cognitive Training (CCT) is an intervention that teaches compensatory cognitive strategies to improve functioning in prospective memory, attention, learning/memory, and executive functioning, along with strategies to reduce stress and improve sleep. The current randomized controlled trial examined the efficacy of CCT compared to a robust control condition, Holistic Cognitive Education (HCE). Post-9/11 Veterans (n = 79) who were homeless or unstably housed and receiving VA residential psychiatric rehabilitation completed assessments at baseline, midpoint (5 weeks), and post-treatment (10 weeks). Veterans were randomized to receive 10 once-weekly, 1-hour manualized individual sessions of either CCT or HCE. Outcome measures included self-reported symptom and functioning ratings and a neuropsychological assessment. Multi-level modeling was used to examine treatment-related improvements in neuropsychological functioning and neurobehavioral symptoms at post-treatment. The models revealed that compared to the HCE group, the CCT group demonstrated greater improvements in attention/vigilance performance (d = 0.89), cognitive symptoms (d=-1.53), and interpersonal functioning (getting along with others; d=-0.87). HCE participants demonstrated greater improvement in speed of processing (a domain not targeted by CCT; d=-0.65). CCT has the potential to improve objective attention/vigilance and self-reported cognitive symptoms and interpersonal difficulties in unstably housed Veterans with complex medical and psychiatric comorbidities.

Indexed as

Ill-Housed PersonsPsychiatric RehabilitationResidential TreatmentStress Disorders, Post-TraumaticVeteransAdultBrain Injuries, TraumaticCognitive TrainingFemaleHumansMaleMiddle AgedNeuropsychological TestsCognitive rehabilitationDepressionHomelessnessPosttraumatic stress disorderTraumatic brain injury

Identifiers

PMID42025611
PMCPMC13245805

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.