Evidence map›Paper›PMID 42024672›Full record

ArticlePloS one2026

A rapid evaluation of quality of sedation and ventilation care processes for critically ill patients in Vietnam.

An Luu Phuoc, Vo Tan Hoang, Truong Ngoc Trung, Nguyen Thien Binh, Vu Dinh Phu, Tran Minh Duc, Ha Thi Hai Duong, Tran Thi Diem Thuy, Duong Bich Thuy, Nguyen Thanh Nguyen and 15 more

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

An Luu PhuocOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Vo Tan HoangOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Truong Ngoc TrungHospital for Tropical diseases, Ho Chi Minh City, Vietnam.
Nguyen Thien BinhTrung Vuong Hospital, Ho Chi Minh City, Vietnam.
Vu Dinh PhuNational Hospital for Tropical Diseases.ORCID https://orcid.org/0000-0002-9767-3396
Tran Minh DucOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Ha Thi Hai DuongHospital for Tropical diseases, Ho Chi Minh City, Vietnam.
Tran Thi Diem ThuyHospital for Tropical diseases, Ho Chi Minh City, Vietnam.
Duong Bich ThuyHospital for Tropical diseases, Ho Chi Minh City, Vietnam.
Nguyen Thanh NguyenHospital for Tropical diseases, Ho Chi Minh City, Vietnam.
Le Thanh ChienTrung Vuong Hospital, Ho Chi Minh City, Vietnam.
Doan Bui Xuan ThyOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Nguyen Hoang VietDong Thap Hospital, Dong Thap, Vietnam.
Bui Ngoc ThanhDong Thap Hospital, Dong Thap, Vietnam.
Vo Thi Hoang Dung EmDong Thap Hospital, Dong Thap, Vietnam.
Jennifer Van NuilOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Abi BeanePandemic Sciences Hub and Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, United Kingdom.
Rashan HaniffaPandemic Sciences Hub and Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, United Kingdom.
Pham Ngoc ThachNational Hospital for Tropical Diseases.
Chau Minh DucDong Thap Hospital, Dong Thap, Vietnam.
Huynh Ngoc HonTrung Vuong Hospital, Ho Chi Minh City, Vietnam.
Nguyen Le Nhu TungHospital for Tropical diseases, Ho Chi Minh City, Vietnam.
Lam Minh YenOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Louise ThwaitesOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Duncan WagstaffUniversity College London, London, United Kingdom.ORCID https://orcid.org/0000-0001-9472-1578

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSedation assessment, spontaneous awakening and breathing trials are evidence-based practices which can minimise harm from ventilation and sedation of critically ill patients. There are known difficulties in implementing these processes which are likely to be exacerbated in low-resource settings. This study aimed to describe current delivery of these care processes in three intensive care units in Vietnam; identify barriers and facilitators to their delivery; and describe local capacity for improvement.

methodsWe conducted a prospective rapid evaluation between 01/11/2021 and 31/12/2023 comprising registry-enabled measurement of daily care processes, process mapping, observations, focus group discussions, semi-structured interviews and a structured assessment of local capacity for improvement. Contextual determinants of care quality were analysed using the Consolidated Framework for Implementation Research. Organisational capacity for improvement was analysed using the Model for Understanding Success in Quality.

resultsSedation was assessed qualitatively rather than using systematic tools. Spontaneous Awakening and Breathing Trials were both performed according to individual doctors' clinical judgement in a non-protocolised manner. Barriers to delivering these processes included the lack of locally-adapted protocols, perceived safety concerns exacerbated by staffing shortages and lack of familiarity due to confusing terminology. Facilitators to improvement included quality improvement champions, registry-enabled audit and feedback, training, and partnerships within and between hospitals.

conclusionWe identified opportunities to improve sedation and ventilation in the three study settings in Vietnam. The barriers to delivering the care processes we studied echoed those reported in high-income countries, but were exacerbated by local contextual factors such as staffing shortages and differences in professional roles. We developed recommendations for future improvement projects: implementing setting-adapted protocols, standardising terminology to improve documentation, engaging clinical staff with feedback, identifying champions, educate staff regarding the clinical processes and quality improvement and leverage existing internal expertise. These recommendations may have applicability to other care processes and/or settings.

Indexed as

Critical IllnessQuality of Health CareRespiration, ArtificialHumansIntensive Care UnitsProspective StudiesQuality ImprovementVietnam

Identifiers

PMID42024672
PMCPMC13105344

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.