Evidence map›Paper›PMID 42024650›Full record

ArticleInternational journal of geriatric psychiatry2026

Development and Cross-Sectional Validation of the Quality of Life and Function Five-Domain Scale (QFS-5) in Dementia-Free Community-Dwelling Older Adults.

Zahinoor Ismail, Ibadat Warring, Dylan X Guan, Pierre Chue, Andrea Bardell, Clive Ballard, Byron Creese, Anne Corbett, Ellie Pickering, Pamela Roach and 1 more

Abstract readValidation Study
In one paragraph

Article in International journal of geriatric psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Zahinoor IsmailHotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-5529-3731
Ibadat WarringHotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Dylan X GuanHotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-7065-1963
Pierre ChueDepartment of Psychiatry, University of Alberta, Edmonton, Alberta, Canada.
Andrea BardellDepartment of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada.
Clive BallardClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK.
Byron CreeseBrunel University, London, UK.ORCID https://orcid.org/0000-0001-6490-6037
Anne CorbettClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK.
Ellie PickeringClinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK.
Pamela RoachHotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Eric E SmithHotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

Funding

Evans Family Fund via the Hotchkiss Brain InstituteGordie Howes CARES
6 · The paper itself

Abstract

introductionQuality of life (QoL) captures objective life conditions, subjective wellbeing, and personal aspirations. Interest is growing in ability-based, patient-centered instruments, not confounded by health outcomes. The Quality of Life and Function Five Domain Scale (QFS-5) uses a multi-dimensional approach to measure QoL emphasizing abilities and life engagement. We describe the development and validation of the QFS-5 in a large sample of community-dwelling older adults.

methodsThe validation sample comprised 1610 participants aged ≥ 50 from the Canadian Platform for Research Online to Investigate Health, Quality of Life, Cognition, Behavior, Function, and Caregiving in Aging (CAN-PROTECT). Internal consistency was assessed using Cronbach's alpha and item-total correlations. Confirmatory factor analysis (CFA) evaluated domain structure. Criterion validity was tested through Pearson's correlation with the EuroQol-5D (EQ-5D). Convergent and discriminant validity were evaluated from associations with cognitive, mental health, and functional measures. Floor and ceiling effects were investigated.

resultsThe QFS-5 demonstrated excellent internal consistency (α = 0.92); CFA supported the proposed domain structure with strong item loadings. Criterion validity was confirmed with correlation of -0.61 against the EQ-5D; higher symptom burden on related scales were associated with lower QFS-5 scores. Floor effects were minimal, while modest ceiling effects were observed in some domains. No significant floor or ceiling effects were found in participants with frailty.

conclusionValidity and reliability are established for this ability-based QoL scale, within a sample of mostly cognitively unimpaired, community-dwelling older adults. The QFS-5 aligns with EQ-5D, demonstrating potential clinical and research utility to measure relevant patient-reported QoL outcomes.

Indexed as

Quality of LifeActivities of Daily LivingAgedAged, 80 and overCanadaCross-Sectional StudiesFactor Analysis, StatisticalFemaleGeriatric AssessmentHumansIndependent LivingMaleMiddle AgedPsychometricsReproducibility of ResultsSurveys and QuestionnairesEQ‐5Dfunctionolder adultsQFS‐5quality of life (QoL)validation

Identifiers

PMID42024650
PMCPMC13105311

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.