Evidence map›Paper›PMID 42024161›Full record

ReviewDer Nervenarzt2026

[Psychiatric challenges in Prader-Willi syndrome].

Christian Karl Eberlein, Maximilian Jakob, Angelina Jechalke, Gesa Ordon

Abstract readEnglish AbstractReview
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In one paragraph

Review in Der Nervenarzt, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christian Karl EberleinKlinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. eberlein.christian@mh-hannover.de.
Maximilian JakobKlinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Angelina JechalkeKlinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Gesa OrdonKlinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrader-Willi syndrome (PWS) is highly associated with psychiatric comorbidity.

objectivesThis article investigates the prevalence of mental disorders in PWS, explores their association with neurobiological foundations, and outlines the resulting clinical recommendations.

methodsAn evaluation of the scientific literature in the context of clinical experience from the special outpatient clinic for mental health in rare syndromic disorders at Hannover Medical School.

resultsPsychiatric manifestations are present in 44-89% of PWS patients, with disruptive behavior, skin picking, psychosis, compulsive symptoms, and affective disorders being the most common. PWS psychosis differs from schizophrenic psychosis and can be difficult to treat in some cases. Treatment approaches exist for disruptive behavior, affective symptoms, and compulsive symptoms.

conclusionsKnowledge of the neurobiological basis of PWS is necessary for the adequate treatment of psychiatric disorders. In addition to pharmacological therapies, behavioral interventions and environmental control should also be included.

Indexed as

Mental DisordersPrader-Willi SyndromeAntipsychotic AgentsComorbidityEvidence-Based MedicineExcoriation DisorderHumansTreatment OutcomeAntipsychotic AgentsAntipsychotic agentsCompulsive behaviorPsychotic disordersSelective serotonin reuptake inhibitorsSkin picking

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.