Evidence map›Paper›PMID 42023851›Full record

ArticleACS applied materials & interfaces2026

Composite Nanoarchitectonics with Turmeric-Functionalized Layered Double Hydroxide/Poly(3-hydroxyoctanoate) as Bioactive Coatings for Bone and Nerve Regeneration.

Katarzyna Haraźna, Sonia Bujok, Kamila Lis, Julita Wesołowska, Maciej Bik, Agnieszka M Tomala, Karina Niziołek, Martina Nevoralová, Justyna Prajsnar, Hynek Beneš and 2 more

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katarzyna HaraźnaDepartment of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., Cracow 31-864, Poland.ORCID 0000-0001-7553-5796
Sonia BujokJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, Cracow 30-239, Poland.
Kamila LisCUT Doctoral School, Department of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., Cracow 31-864, Poland.
Julita WesołowskaLaboratory of Microscopic Imaging, Maj Institute of Pharmacology, Polish Academy of Sciences, CEPHARES, 12 Smętna Street, Cracow 31-343, Poland.
Maciej BikFaculty of Materials Science and Ceramics, AGH University of Krakow, Kraków 30-059, Poland.ORCID 0000-0003-0921-8797
Agnieszka M TomalaDepartment of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., Cracow 31-864, Poland.
Karina NiziołekDepartment of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., Cracow 31-864, Poland.
Martina NevoralováInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6 162 00, Czech Republic.
Justyna PrajsnarJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, Cracow 30-239, Poland.
Hynek BenešInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6 162 00, Czech Republic.ORCID 0000-0002-6861-1997
Maciej GuzikJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, Cracow 30-239, Poland.
Agnieszka Sobczak-KupiecDepartment of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., Cracow 31-864, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited regenerative capacity of bone and peripheral nerve tissues, together with the insufficient bioactivity and immunomodulatory control of commercially available coating materials, drives the development of multifunctional biomaterials capable of modulating cellular and immune responses. Herein, bacterially derived poly(3-hydroxyoctanoate) (P(3HO)) was applied as a biodegradable matrix for nanocomposites incorporating layered double hydroxides (LDHs) and their turmeric (turm)-functionalized counterparts. Nanocomposite films containing 2 wt.% nanofillers were fabricated by solvent casting. Structural and physicochemical analyses confirmed successful functionalization (up to 60 wt.% turm), with a tendency to form microscale agglomerates within the polymer matrix. These agglomerates contributed to heterogeneous surface topography (R

Indexed as

Bone RegenerationCoated Materials, BiocompatibleHydroxidesNanocompositesNerve RegenerationPolyestersAnimalsCell ProliferationCell SurvivalMiceRatsCoated Materials, BiocompatibleHydroxidesPolyestersbone tissue engineeringlayered double hydroxidesnerve tissue engineeringpoly(3-hydroxyoctanoate)turmeric

Identifiers

PMID42023851
PMCPMC13308884

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.