Evidence map›Paper›PMID 42023824›Full record

ArticleAutophagy2026

Depletion of TECPR2 leads to mitochondrial failure associated with neurodegeneration.

Madhuri Chaurasia, Milana Fraiberg, Nemanja Subic, Oren Shatz, Kamilya Kokabi, Olee Gogoi, Olena Trofimyuk, Bat Chen Tamim-Yecheskel, Saskia Freud, Alik Demishtein and 7 more

Abstract read
In one paragraph

Article in Autophagy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Madhuri ChaurasiaDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0001-8701-2255
Milana FraibergDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Nemanja SubicDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Oren ShatzDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Kamilya KokabiDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Olee GogoiDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Olena TrofimyukDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Bat Chen Tamim-YecheskelDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Saskia FreudDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Alik DemishteinDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Ekaterina KopitmanDepartment of Life Science Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Inna GoliandDepartment of Life Science Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Sabita ChourasiaDepartment of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.
Yoav PelegStructural Proteomics Unit, Department of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Elena AinbinderDepartment of Life Science Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Nili DezorellaIrving and Cherna Moskowitz Center for Nano and Bio-Nano Imaging, Weizmann Institute of Science, Rehovot, Israel.
Zvulun ElazarDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HSAN9 is a rare progressive neurodegenerative disease in children linked to bi-allelic loss-of-function mutations in the

Indexed as

MitochondriaNeurodegenerative DiseasesAnimalsFibroblastsGanglia, SpinalHumansIntegrated Stress ResponseMiceMitophagyReactive Oxygen SpeciesReactive Oxygen SpeciesHSAN9integrated stress responsemitophagyneurodegenerationTECPR2unfolded protein response

Identifiers

PMID42023824
PMCPMC13557572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.