Evidence map›Paper›PMID 42023738›Full record

ArticleAlimentary pharmacology & therapeutics2026

A Care Pathway for the Treatment of IBD Reduces Healthcare Costs and Is Cost-Effective: Results of the Multicentre IBD Value Study.

Elyke H Visser, Martijn A Oude Voshaar, Reinier C A van Linschoten, Alexander G L Bodelier, Claire Fitzpatrick, Vincent de Jonge, Hestia Vermeulen, K Evelyne Verweij, Sanne van der Wiel, Daniëlle van der Horst and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Alimentary pharmacology & therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elyke H VisserDepartment of Gastroenterology & Hepatology, Franciscus Hospital, Rotterdam, the Netherlands.ORCID https://orcid.org/0000-0002-6259-4954
Martijn A Oude VoshaarDepartment of Public Health, Erasmus MC, Rotterdam, the Netherlands.
Reinier C A van LinschotenDepartment of General Practice, Erasmus MC, Rotterdam, the Netherlands.
Alexander G L BodelierDepartment of Gastroenterology & Hepatology, Amphia Hospital, Breda, the Netherlands.
Claire FitzpatrickDepartment of Gastroenterology & Hepatology, IJsselland Hospital, the Netherlands.
Vincent de JongeDepartment of Gastroenterology & Hepatology, Albert Schweitzer Hospital, Dordrecht, the Netherlands.
Hestia VermeulenDepartment of Gastroenterology & Hepatology, Ikazia Hospital, Rotterdam, the Netherlands.
K Evelyne VerweijDepartment of Gastroenterology & Hepatology, Maasstad Hospital, Rotterdam, the Netherlands.
Sanne van der WielDepartment of Gastroenterology & Hepatology, Reinier De Graaf Gasthuis, Delft, the Netherlands.
Daniëlle van der HorstCrohn & Colitis NL, Woerden, the Netherlands.
C Janneke van der WoudeDepartment of Gastroenterology & Hepatology, Erasmus MC, Rotterdam, the Netherlands.
R L WestDepartment of Gastroenterology & Hepatology, Franciscus Hospital, Rotterdam, the Netherlands.
D van NoordDepartment of Gastroenterology & Hepatology, Franciscus Hospital, Rotterdam, the Netherlands.

Funding

AbbVieCelltrionDr. Falk PharmaEli Lilly and CompanyFerringGalapagosJanssen PharmaceuticalsMerck Sharp and DohmePfizerTakeda Pharmaceutical Company
6 · The paper itself

Abstract

backgroundAn advanced therapy care pathway (ACP) for the treatment of patients with IBD can reduce practice variation and improve outcomes.

aimsThis study aimed to estimate the effect of the ACP on costs and quality of life, and to assess the cost-effectiveness of the ACP.

methodsA cost-utility and cost-effectiveness analysis was conducted from a societal perspective. The ACP was implemented in six hospitals, and two hospitals in the same region served as controls. Costs and quality of life were assessed during a baseline period (December 2020-December 2021) and an intervention period after implementing the ACP (March 2022-March 2023). Quality-adjusted life years (QALYs) were derived from the EQ-5D-5L; disease control from the IBD-Control questionnaire. A difference-in-differences (DiD) analysis was conducted, and the net monetary benefit and incremental cost-effectiveness ratio (ICER) were calculated.

resultsIn total, 1,173 patients were included (intervention n = 841, control n = 332). Baseline costs per patient were €23,259.96 in the intervention hospitals and €22,837.93 in the control hospitals. During the intervention period, costs decreased to €20,959.76 in intervention hospitals. This reduction was not observed in control hospitals (€22,191.21). The DiD-analysis showed cost savings of -€1933.69; QALYs (0.001) and disease control (0.15) did not change. The ICER indicated cost savings without compromising quality of life or disease control.

conclusionsThe implementation of an ACP for the treatment of patients with IBD reduces costs, maintains quality of life and disease control, and is cost-effective. These results emphasise that the implementation of care pathways in current practices should be considered. TRIAL REGISTRATION NUMBER: NL-OMON21751. Website: Value-based healthcare for Inflammatory Bowel Disease: Improving (cost-) effectiveness.

Indexed as

Critical PathwaysHealth Care CostsInflammatory Bowel DiseasesAdultAgedCost-Benefit AnalysisCost-Effectiveness AnalysisFemaleHumansMaleMiddle AgedQuality-Adjusted Life YearsQuality of LifeSurveys and Questionnairesadvanced therapiescare pathwaycost‐effectivenessinflammatory bowel diseasevalue‐based healthcare

Identifiers

PMID42023738
PMCPMC13356313

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.