Evidence map›Paper›PMID 42023400›Full record

ArticleResearch and practice in thrombosis and haemostasis2026

Postpartum well-being in hemophilia carriers and women with von Willebrand disease: insights from patient-reported outcome measures.

Anne de Vaan, Elke A Doeff, Jeroen Eikenboom, Marieke J H A Kruip, Marieke C Punt, Michiel Coppens, Laurens Nieuwenhuizen, Saskia E M Schols, Anja B U Mäkelburg, Floor C J I Heubel-Moenen and 6 more

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Article in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Anne de VaanDivision of Internal Medicine and Dermatology, Center for Benign Haematology, Thrombosis and Haemostasis, van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Elke A DoeffDivision of Internal Medicine and Dermatology, Center for Benign Haematology, Thrombosis and Haemostasis, van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Jeroen EikenboomDepartment of Internal Medicine, Division of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, Netherlands.
Marieke J H A KruipDepartment of Hematology and department of Quality and Patient Care, Erasmus MC, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Marieke C PuntDivision of Internal Medicine and Dermatology, Center for Benign Haematology, Thrombosis and Haemostasis, van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Michiel CoppensDepartment of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Laurens NieuwenhuizenDepartment of Haematology, Maxima Medisch Centrum, Veldhoven, Netherlands.
Saskia E M ScholsDepartment of Hematology, Radboud University Medical Center and Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Nijmegen, Netherlands.
Anja B U MäkelburgDepartment of Hematology, University Medical Center Groningen, Groningen, Netherlands.
Floor C J I Heubel-MoenenDepartment of Hematology-Internal Medicine, Maastricht University Medical Center+ and Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht and CARIM, Maastricht University, Maastricht, Netherlands.
Hans J DuvekotDepartment of Obstetrics, Erasmus MC, Erasmus University Medical Center, Rotterdam, Netherlands.
Marjolein PetersDepartment of Pediatric Hematology, Emma Children's Hospital, University Medical Centers, Location AMC, Amsterdam, Netherlands.
Annemieke MiddeldorpDepartment of Obstetrics, Leiden University Medical Center, Leiden, Netherlands.
Kitty W M BloemenkampDepartment of Obstetrics, WKZ Birth Centre, Division Woman and Baby, University Medical Center Utrecht, Utrecht, Netherlands.
Roger E G SchutgensDivision of Internal Medicine and Dermatology, Center for Benign Haematology, Thrombosis and Haemostasis, van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Karin P M van GalenDivision of Internal Medicine and Dermatology, Center for Benign Haematology, Thrombosis and Haemostasis, van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hemophilia carriers (HCs) and women with von Willebrand disease (VWD) receive specialized obstetric care because of a higher chance for postpartum bleeding and potential bleeding in the neonates. It is unknown what their postpartum quality of life (QoL), childbirth satisfaction, and experience are and how this differs from the general population. Objectives: This study assessed QoL, childbirth satisfaction and experience in HCs and women with VWD at week 1 and 6 postpartum. These outcomes are compared with those from retrospective studies of the general population. Methods: Participants completed 3 patient-reported outcome measures postpartum: the Short Form-36 at week 1 and 6 measuring QoL, the Mackey Childbirth Satisfaction Rate Scale at week 1 for childbirth satisfaction, and the Labor and Delivery Index at week 6 for childbirth experience. Descriptive statistics were used. Results: In total, 85 HCs and 81 women with VWD completed ≥1 questionnaire. Pain and physical functioning improved over time (both moderate to fairly well; Conclusion: HCs and women with VWD recover less between week 1 and 6 postpartum than the general population. HCs report more worries about their child during childbirth than women with VWD and the general population.

Indexed as

Hemophilia APatient Reported Outcome MeasuresPostpartum Periodvon Willebrand DiseasesAdultFemaleHeterozygoteHumansPatient SatisfactionPostpartum HemorrhagePregnancyQuality of LifeRetrospective StudiesSurveys and QuestionnairesYoung Adulthemophiliapatient-reported outcome measurespostpartum periodquality of lifevon Willebrand disease

Identifiers

PMID42023400
PMCPMC13098571

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.