Evidence map›Paper›PMID 42023158›Full record

ArticleiScience2026

The influence of murine cytomegalovirus infection on susceptibility to mycobacterial infection.

Shuailin Li, Claire Hutchings, Marcellus Korompis, Christopher De Voss, Alberta Ateere, Iman Satti, Paul Klenerman, Helen McShane, Elena Stylianou

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuailin LiThe Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.
Claire HutchingsPeter Medawar Building for Pathogen Research and Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX1 3SY, UK.
Marcellus KorompisThe Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.
Christopher De VossThe Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.
Alberta AteereThe Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.
Iman SattiThe Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.
Paul KlenermanPeter Medawar Building for Pathogen Research and Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX1 3SY, UK.
Helen McShaneThe Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.
Elena StylianouThe Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) infection has been associated with an increased risk of tuberculosis, but the underlying mechanisms remain unclear. Here, we used the murine CMV (MCMV), a virus genetically and biologically related to human CMV, to interrogate potential mechanisms. MCMV-infected macrophages showed reduced expression of CD80, CD86, and MHC class II, decreased phagocytosis of mycobacteria, and enhanced mycobacterial killing compared with MCMV-uninfected macrophages. Splenocytes from MCMV-infected mice better controlled mycobacterial growth

Indexed as

bacteriologydiseaseimmunologyviral microbiology

Identifiers

PMID42023158
PMCPMC13098500

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.