Evidence map›Paper›PMID 42023109›Full record

ArticleFrontiers in medicine2026

Endothelial adenosine A

Ying Qian, Meigui Hu, Xingxing Xie, Li Ren, Xiaorong Huang, Shanshan Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying QianDepartment of Pharmacy, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Meigui HuDepartment of Pulmonary and Critical Care Medicine, The Fourth People's Hospital of Guiyang City, Guiyang, China.
Xingxing XieWest China School of Pharmacy, Sichuan University, Chengdu, China.
Li RenGood Clinical Practice Center, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Xiaorong HuangGood Clinical Practice Center, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Shanshan HuGood Clinical Practice Center, Affiliated Hospital of Zunyi Medical University, Zunyi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methamphetamine (METH), a psychostimulant, can cause the blood-brain barrier (BBB) breakdown through astrocyte endfeet swelling and endothelial cell impairment. Our previous studies have shown that phosphorylated microtubule-associated protein Tau (p-Tau) levels increase, especially in neurons, after METH exposure. However, whether p-Tau accumulates in the endothelial cells of METH mouse brains remains unclear. The effects of endothelial p-Tau accumulation on BBB integrity in a chronic METH mouse model are elusive. Methods: The A Results: In this study, we found that METH might induce the upregulation of adenosine receptor subtype 2A (A Discussion: Based on these findings, we propose an A

Indexed as

adenosine receptorblood brain barriermethamphetaminemicrotubule associated protein taumicrovessel endothelial cell

Identifiers

PMID42023109
PMCPMC13095544

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.