Evidence map›Paper›PMID 42022961›Full record

ReviewRSC advances2026

Chitosan-cellulose hydrogels: advances in stimuli-responsive biomedical therapeutics.

Nesa Rafati, Atefeh Zarepour, Arezoo Khosravi, Siavash Iravani, Ali Zarrabi

Abstract readReview
In one paragraph

Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nesa RafatiDepartment of Biotechnology, Faculty of Biological Sciences, Alzahra University Tehran, 1953833511 Iran.
Atefeh ZarepourDepartment of Biology, Faculty of Arts and Sciences, Kocaeli University Izmit Kocaeli 41001 Türkiye.
Arezoo KhosraviDepartment of Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, Istanbul Okan University Istanbul 34959 Türkiye.
Siavash IravaniIndependent Researcher W Nazar ST, Boostan Ave Isfahan Iran siavashira@gmail.com.ORCID https://orcid.org/0000-0003-3985-7928
Ali ZarrabiDepartment of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Istinye University Istanbul 34396 Türkiye alizarrabi@gmail.com.ORCID https://orcid.org/0000-0003-0391-1769

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chitosan-cellulose hydrogels have emerged as versatile stimuli-responsive biomaterials for biomedical therapeutics, combining the antimicrobial, mucoadhesive, and pH-sensitive properties of chitosan with the mechanical strength, high water retention, and biodegradability of cellulose. These hybrid systems have demonstrated significant potential in controlled drug delivery, tissue engineering, and regenerative medicine, enabling sustained and localized therapeutic release while reducing systemic toxicity in cancer and chronic disease management. Despite these advantages, important challenges remain regarding long-term

Identifiers

PMID42022961
PMCPMC13096887

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.