Evidence map›Paper›PMID 42022868›Full record

ArticleSmall science2026

A Nanotube Injector for Cytoplasmic Transfer and Enhanced Mitochondrial Function.

Bingfu Liu, Zhuhang Dai, Bowen Zhang, Kazuhiro Oyama, Chenxi Li, Yukun Chen, Mingyin Cui, Takeo Miyake

Abstract read
In one paragraph

Article in Small science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bingfu LiuGraduate School of Information Waseda University Kitakyushu Fukuoka Japan.ORCID https://orcid.org/0009-0008-2434-6299
Zhuhang DaiGraduate School of Information Waseda University Kitakyushu Fukuoka Japan.
Bowen ZhangGraduate School of Information Waseda University Kitakyushu Fukuoka Japan.
Kazuhiro OyamaGraduate School of Information Waseda University Kitakyushu Fukuoka Japan.ORCID https://orcid.org/0009-0009-3370-7655
Chenxi LiGraduate School of Information Waseda University Kitakyushu Fukuoka Japan.
Yukun ChenGraduate School of Information Waseda University Kitakyushu Fukuoka Japan.
Mingyin CuiGraduate School of Information Waseda University Kitakyushu Fukuoka Japan.
Takeo MiyakeGraduate School of Information Waseda University Kitakyushu Fukuoka Japan.ORCID https://orcid.org/0000-0002-7445-633X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intercellular transportation of molecules is crucial for regulating cell communication and function. However, the existing techniques for molecule transfer across cell barriers often cause cellular damage or have low transfer efficiencies. To address these limitations, this study proposes an innovative nanotube membrane-based injector (nanoinjector) system capable of extracting diverse cytoplasmic molecules from source cells and transferring them to target cells. The developed system demonstrates high efficiency, with over 95% viability and 90% transfer efficiency. Additionally, it enables mitochondrial transfer, which enhances cellular adenosine triphosphate (ATP) production by up to 25% within 24 h. This study explores the impact of intracellular content transport, enabled by this new tool, on cellular activities, with promising implications for cell surgery and therapy.

Indexed as

adenosine triphosphate synthesismitochondria transfermolecular deliverynanotubes membrane

Identifiers

PMID42022868
PMCPMC13097451

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.