Evidence map›Paper›PMID 42022813›Full record

Observational studyFrontiers in public health2026

Microplastics in neonates: an overlooked cost of parenteral nutrition.

Debo Xu, Zhenyu Liang, Qiaohuan Yang, Lin Li, Huiyi Li, Chuming You, Qiong Meng, Wei Zhou

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07326761 (Microplastic Exposure in Neonates Receiving Parenteral Nutrition), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07326761 nacompletednot on this map

Microplastic Exposure in Neonates Receiving Parenteral Nutrition: A Prospective Cohort Study in the NICU

TypeinterventionalSponsorHuiyi LiRan2025 to 2025Enrolled12ConditionsMicroplastics ExposureArmsNo Intervention: Observational Cohort
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Debo Xu *Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Zhenyu Liang *Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Qiaohuan Yang *Department of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Lin LiDepartment of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Huiyi LiDepartment of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Chuming YouDepartment of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Qiong MengDepartment of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Wei ZhouDepartment of Pediatrics, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Microplastics (MPs) are emerging contaminants that raise concerns due to their potential health effects on vulnerable neonates who may be exposed to medical devices. Methods: This prospective study investigated the presence of MPs in neonatal blood in relation to parenteral nutrition (PN) duration. A total of 12 neonates were categorized into long-term (>14 days), short-term (3-7 days), and non-exposed control groups. MPs were analyzed using confocal micro-Raman spectroscopy. Results: Polyethylene accounted for 95.65% of particles detected in all blood samples. MP abundance was significantly higher in the long-term PN group compared to both short-term and control groups ( Discussion: These preliminary findings, derived from a small sample cohort, suggest that the PN system may serve as a potential iatrogenic source of MPs for neonates. Clinical trial registration: NCT07326761.

Indexed as

MicroplasticsParenteral NutritionFemaleHumansInfant, NewbornMaleProspective StudiesMicroplasticsdose–response relationshipiatrogenic exposuremicroplasticsneonatesparenteral nutrition

Identifiers

PMID42022813
PMCPMC13096745

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.