Evidence map›Paper›PMID 42022750›Full record

ArticleInternational journal of analytical chemistry2026

Eco-Conscious RP-HPLC Method for Concurrent Quantification of Assay and Dissolution Testing of Methocarbamol and Diclofenac Potassium in Tablet Formulations.

Hedia Ouni, Fahad M Alminderej, Mostafa E Salem, Sayed M Saleh, Omkulthom Al Kamaly, Mahmoud A Mohamed

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hedia OuniDepartment of Chemistry, College of Science in Yanbu, Taibah University, Yanbu Governorate, Saudi Arabia, taibahu.edu.sa.ORCID https://orcid.org/0009-0006-4317-3181
Fahad M AlminderejDepartment of Chemistry, College of Science, Qassim University, Buraidah, 51452, Saudi Arabia, qu.edu.sa.ORCID https://orcid.org/0000-0002-3649-0190
Mostafa E SalemDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia, imamu.edu.sa.ORCID https://orcid.org/0000-0003-4341-410X
Sayed M SalehDepartment of Chemistry, College of Science, Qassim University, Buraidah, 51452, Saudi Arabia, qu.edu.sa.ORCID https://orcid.org/0000-0002-2677-0439
Omkulthom Al KamalyDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia, pnu.edu.sa.ORCID https://orcid.org/0000-0003-4706-4311
Mahmoud A MohamedHikma Pharmaceutical Company, Beni-Suef, 62511, Egypt.ORCID https://orcid.org/0000-0003-3946-5465

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A common combination of methocarbamol (MTH) and diclofenac potassium (DCL K) relieves musculoskeletal pain and inflammation through centrally acting muscle relaxants. A dual-function RP-HPLC method was used to analyze the assay and dissolution testing of MTH and DCL K simultaneously. As part of the suggested method, green and white analytical chemistry standards were incorporated to ensure sustainability and compatibility. We performed a chromatographic separation on a C8 column (15 cm × 4.6 mm, 5 μm) with a mobile phase of phosphate buffer and ethanol (30:70

Indexed as

Analytical Eco-Scaleanti-inflammatory and analgesic effectsassay and dissolution testingCACIdiclofenac KEPPImethocarbamolRP-HPLC

Identifiers

PMID42022750
PMCPMC13096726

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.