Evidence map›Paper›PMID 42022738›Full record

ArticleNanoscale advances2026

Biomarker-targeted functionalized magnetic nanoparticles: synthesis and aptamer conjugation optimization toward Alzheimer's disease biosensing.

Antonios Makridis, Konstantina Kazeli, Georgios Katsipis, Eleni E Tzekaki, Anastasia A Pantazaki, Cristian Bosch, Ricardo Simon-Carbajo, Makis Angelakeris

Abstract read
In one paragraph

Article in Nanoscale advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonios MakridisMagnetic Nanostructure Characterization: Technology & Applications, Centre for Interdisciplinary Research and Innovation, Aristotle University Thessaloniki 57001 Greece anmakrid@physics.auth.gr.ORCID https://orcid.org/0000-0002-7609-1362
Konstantina KazeliMagnetic Nanostructure Characterization: Technology & Applications, Centre for Interdisciplinary Research and Innovation, Aristotle University Thessaloniki 57001 Greece anmakrid@physics.auth.gr.ORCID https://orcid.org/0000-0002-7426-3706
Georgios KatsipisLaboratory of Neurodegenerative Diseases, Centre for Interdisciplinary Research and Innovation, Aristotle University Thessaloniki 57001 Greece.ORCID https://orcid.org/0000-0001-7917-3243
Eleni E TzekakiLaboratory of Neurodegenerative Diseases, Centre for Interdisciplinary Research and Innovation, Aristotle University Thessaloniki 57001 Greece.ORCID https://orcid.org/0000-0002-1525-8333
Anastasia A PantazakiLaboratory of Neurodegenerative Diseases, Centre for Interdisciplinary Research and Innovation, Aristotle University Thessaloniki 57001 Greece.ORCID https://orcid.org/0000-0003-3791-6955
Cristian BoschIreland's Centre for Artificial Intelligence (CeADAR), University College Dublin Belfield D04 V2N9 Dublin Ireland.ORCID https://orcid.org/0000-0002-2962-4226
Ricardo Simon-CarbajoIreland's Centre for Artificial Intelligence (CeADAR), University College Dublin Belfield D04 V2N9 Dublin Ireland.ORCID https://orcid.org/0000-0002-2121-2841
Makis AngelakerisMagnetic Nanostructure Characterization: Technology & Applications, Centre for Interdisciplinary Research and Innovation, Aristotle University Thessaloniki 57001 Greece anmakrid@physics.auth.gr.ORCID https://orcid.org/0000-0001-9109-0221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic-plasmonic hybrid nanoparticles are gaining prominence in biomedical diagnostics due to their dual functionality, combining magnetic manipulation and signal enhancement. A major challenge remains the reproducible synthesis of core-shell nanostructures with controlled size, composition, and stability. In this work, we present a robust two-step aqueous co-precipitation method to produce gold/magnetite nanoparticles, for early Alzheimer's disease diagnosis, based on biomarker's aptamer-based biosensing. Magnetite nanoparticles were first synthesized with high saturation magnetization, followed by controlled gold shell growth

Identifiers

PMID42022738
PMCPMC13096835

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.