Evidence map›Paper›PMID 42022591›Full record

ArticleHealth science reports2026

Elevated Salivary Antioxidant Biomarkers are Favorable for Clinical Pregnancy in Women Undergoing IVF: A Prospective Cohort Study.

Mahdieh Ghafarpoor, Narges Gholizadeh, Ashraf Alyasin, Iraj Mirzaii-Dizgah, Mohadeseh Bahmaee, Nafiseh Sheykhbahaei

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahdieh GhafarpoorDepartment of Oral & Maxillofacial Medicine, School of Dentistry Bushehr University of Medical Science Tehran Iran.ORCID https://orcid.org/0000-0002-2021-3607
Narges GholizadehDepartment of Oral & Maxillofacial Medicine, School of Dentistry Tehran University of Medical Science Tehran Iran.ORCID https://orcid.org/0000-0003-2006-8240
Ashraf AlyasinDepartment of Infertility, Shariati Hospital Tehran University of Medical Sciences Tehran Iran.
Iraj Mirzaii-DizgahDepartment of Physiology, School of Medicine Aja University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0003-3488-6842
Mohadeseh BahmaeeSchool of Dentistry Tehran University of Medical Science Tehran Iran.
Nafiseh SheykhbahaeiDepartment of Oral & Maxillofacial Medicine, School of Dentistry Tehran University of Medical Science Tehran Iran.ORCID https://orcid.org/0000-0003-3869-7256

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: The imbalance of oxidants and antioxidants mediates cell damage through a phenomenon known as oxidative stress. The increase in fertility problems led to a growing focus on factors that affect the outcome of reproductive- assisted treatments. This study aimed to investigate the levels of oxidant-antioxidants in serum and saliva, as systemic sources of oxidative stress, in relation to the outcome of in vitro fertilization (IVF) treatment. Methods: This study was conducted on 80 women who were candidates for frozen embryo transfer. Serum and saliva samples were collected from these individuals according to standardized protocols before embryo transfer. The levels of MDA, SOD, TOC, and TAC in serum and saliva were measured using ELISA kits, and the relationship between these biomarkers and IVF outcomes was evaluated using Results: The serum and salivary SOD and TAC were significantly higher ( Conclusion: The women with positive β-hCG had elevated levels of antioxidants and decreased levels of oxidant biomarkers in both serum and saliva. Further research is needed to confirm saliva as a readily available medium for predicting IVF treatment outcomes.

Indexed as

antioxidantsin vitro fertilizationoxidantsoxidative stresssaliva

Identifiers

PMID42022591
PMCPMC13097343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.