ArticleFrontiers in chemistry2026
Article in Frontiers in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Phyto-synthesized silver-iron oxide nanoparticles fromFrontiers in chemistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Silver nanoparticles are potent nanomaterials with significant applications in combating microbial infections and cancer. In this study, the extract of Gazania rigens var. uniflora was evaluated as a biogenic agent for the synthesis (G-AgNPs), and their biological activity was systematically assessed. Additionally, association of the antibiotic ampicillin and biogenic silver nanoparticles was developed to explore potential additive antibacterial effects, which has not been previously reported for this species. Methods: Silver nanoparticles were synthesized using a combination of the plant leaf extract and silver nitrate solution. Several characterization techniques, including dynamic light scattering (DLS), transmission electron Microscope (TEM), energy-dispersive X-ray spectroscopy (EDX), and Fourier transform infrared (FTIR) spectroscopy, were employed to analyze the synthesized nanoparticles. Results: DLS results indicated the presence of spherical, monodispersed nanoparticles with a mean diameter of 135.4 nm and a polydispersity index of 0.223, while TEM revealed sizes ranging from 14 to 44 nm. FTIR and EDX analyses confirmed the presence of phytochemical capping agents and elemental silver, supporting successful green synthesis. Both biogenic silver nanoparticles and ampicillin-associated G-AgNPs demonstrated antibacterial activity against Staphylococcus aureus, Streptococcus mutans, and Escherichia coli, with the ampicillin-associated G-AgNPs exhibiting a partial additive effect. Cytotoxicity assays demonstrated that G-AgNPs exerted significantly higher toxicity toward the breast cancer cell line MDA-MB-231 compared to non-cancerous breast epithelial cells. Discussion: Overall, this work distinguishes itself by integrating detailed physicochemical characterization with both antibacterial and anticancer evaluations, as well as by examining antibiotic-associated G-AgNPs synthesized using G. rigens. These findings support the potential biomedical relevance of G. rigens-derived AgNPs and justify further mechanistic and in vivo investigations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.