Evidence map›Paper›PMID 42022553›Full record

ArticleFrontiers in nutrition2026

Selective anticancer activity of

Essam Y Abdul-Hafeez, Omer H M Ibrahim, Hani A Alfheeaid, Hassan Barakat

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Essam Y Abdul-HafeezDepartment of Plant Production, College of Agriculture and Food, Qassim University, Buraydah, Qassim, Saudi Arabia.
Omer H M IbrahimDepartment of Agriculture, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Hani A AlfheeaidDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah, Qassim, Saudi Arabia.
Hassan BarakatDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah, Qassim, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: The methanolic extract was subjected to preliminary phytochemical screening for key secondary metabolites. Total phenolic and flavonoid contents were quantified using Folin-Ciocalteu and aluminum chloride colorimetric methods, respectively. The antioxidant capacity was evaluated through the DPPH free radical scavenging assay. Antibacterial and antifungal activities were determined by the agar well diffusion method against pathogenic strains. The cytotoxic and selectivity profiles were assessed using MTT assays on human cancer cell lines (MCF-7, PC-3, Caco-2) and normal Vero cells, with doxorubicin serving as a positive control. Results: Qualitative screening revealed the presence of tannins, alkaloids, glycosides, flavonoids, and terpenoids. The extract exhibited strong antioxidant potential with an IC Discussion: The findings underscore the potent antioxidant, antimicrobial, and selective anticancer properties of

Indexed as

antimicrobial activityantioxidant activitycancer cell linescytotoxicityfood supplyVachellia nilotica

Identifiers

PMID42022553
PMCPMC13095839

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.