ReviewFrontiers in oncology2026
Mechanistic insights into the role of oral microbiome in the malignant transformation of oral lichen planus to oral squamous cell carcinoma.
Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Oral Lichen Planus (OLP) is a common oral potentially malignant disorder, and its transformation into Oral Squamous Cell Carcinoma (OSCC) has become a research focus. In recent years, increasing attention has been paid to the role of the oral microbiome in tumor initiation and progression. Studies have shown that dysbiosis of the oral microbiome may contribute to and accelerate the malignant transformation of OLP to OSCC through multiple mechanisms, including the induction of inflammatory responses, disruption of immune regulation, promotion of oxidative stress, and epithelial-mesenchymal transition (EMT). This review summarizes recent advances in research on the characteristic changes in the oral microbiome and associated molecular mechanisms during the malignant transformation of OLP, aiming to provide a theoretical basis and scientific support for early warning and microecological-targeted interventions in OLP malignancy.
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