Evidence map›Paper›PMID 42022314›Full record

ArticleFrontiers in oncology2026

Past, present and future of nivolumab: new horizons in immuno-oncology.

Inamul Hasan Madar, Sreeshma Ravindran Kammarambath

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Inamul Hasan MadarCentre for Integrative Omics Data Science (CIODS), Yenepoya (Deemed to be University), Mangalore, Karnataka, India.
Sreeshma Ravindran KammarambathCentre for Integrative Omics Data Science (CIODS), Yenepoya (Deemed to be University), Mangalore, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last two years, nivolumab (an inhibitor of programmed death-protein 1, PD-1) has established itself as a cornerstone of modern-day cancer immunotherapy. The immuno-oncology field is developing at an accelerated rate, as nivolumab is progressively acting as an optimally strategic, globally diffused treatment base across a heterogeneous spectrum of malignancies. This has been driven by the accruing data on pivotal phase 3 trials that show better survival rates alongside subsequent regulatory approvals both at the national and international levels that have expanded its therapeutic indications. Meanwhile its translational and clinical impact has been increased further by expanded-access programmes and new combinatorial approaches. All these developments highlight the increasing clinical relevance of nivolumab as they also highlight the current issues in the provision of equitable access, in performing biomarker-based patient stratification, and in optimizing therapeutic sequencing in the rapidly evolving framework of precision oncology.

Indexed as

biosimilarcancerFDAnivolumabPD-1

Identifiers

PMID42022314
PMCPMC13095539

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.