ArticleTanaffos2025
Comparison between Levofloxacin and Azithromycin in Short-term Spirometry and Oxygen Saturation Indices in Patients with Exacerbated Bronchiectasis: A Randomized Double-blind Clinical Trial.
Article in Tanaffos, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Background: Bronchiectasis is a chronic pulmonary disease characterized by abnormal and permanent dilatation of the airways in the lung. This study was conducted to compare the effect of levofloxacin with azithromycin in improving the lung function of these patients. Materials and Methods: In this parallel double-blinded randomized clinical trial, 72 patients with exacerbated bronchiectasis were included and randomly divided into two intervention groups. One group was treated with levofloxacin (500 mg daily for two weeks at first and then 250 mg daily in the next four weeks), and the other group with azithromycin (500 mg daily in the first two weeks and then with a dose of 250 mg daily for the next four weeks) for 6 weeks. The pulmonary function tests were performed and analyzed at the beginning of the study, two, four, and six weeks after the intervention. Results: The mean expiratory volume in the first second (FEV1) and the percentage of oxygen saturation (O Conclusion: The present study showed that the favorable effect of six-week therapy with levofloxacin compared to azithromycin can significantly increase the pulmonary values of FEV1 and O
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