Evidence map›Paper›PMID 42022261›Full record

ReviewAustralian prescriber2026

Cytomegalovirus in pregnancy: prevention, maternal screening, and the role of antivirals.

Lisa Hui, Natasha E Holmes, Michelle L Giles, William Rawlinson

Abstract readReview
In one paragraph

Review in Australian prescriber, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lisa HuiMercy Hospital for Women, Melbourne.ORCID https://orcid.org/0000-0002-9720-3562
Natasha E HolmesMercy Hospital for Women, Melbourne.ORCID https://orcid.org/0000-0001-8501-4054
Michelle L GilesMercy Hospital for Women, Melbourne.ORCID https://orcid.org/0000-0003-3007-1822
William RawlinsonMercy Hospital for Women, Melbourne.ORCID https://orcid.org/0000-0003-0988-7827

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) is the most common congenital infection in Australia and a leading cause of preventable childhood disability. Current Australian guidelines recommend targeted antenatal screening of women at higher risk for CMV infection. Serology testing should also be considered in women with clinical symptoms suggestive of CMV. Women with suspected CMV infection in pregnancy should be promptly referred to a maternal-fetal medicine or infectious diseases specialist. High-dose valaciclovir can reduce in utero transmission to the fetus following first-trimester maternal primary infection; however, long-term safety data are limited. Valaciclovir should only be prescribed by clinicians with specific expertise in CMV, such as maternal-fetal medicine or infectious diseases specialists. Universal hygiene counselling, targeted screening, careful timing of conception after infection, and structured psychological support are essential components of care.

Indexed as

antenatal screeningcytomegalovirusfetusinfectionpregnancyvalaciclovir

Identifiers

PMID42022261
PMCPMC13095495

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.