Evidence map›Paper›PMID 42022235›Full record

ArticleThe journal of poultry science2026

Involvement of Fibro-Adipogenic Progenitors and Cellular Communication Network Family Signaling in the Impaired Muscle Regeneration of Wooden Breast.

Ryosuke Kobayashi, Marina Hosotani, Karin Saito, Yukitaka Masuda, Takeshi Kawasaki, Naoki Takahashi, Yasuhiro Hasegawa, Tomohito Iwasaki, Takafumi Watanabe

Abstract read
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Article in The journal of poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryosuke KobayashiLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
Marina HosotaniLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
Karin SaitoLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
Yukitaka MasudaLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
Takeshi KawasakiResearch Office Concerning the Health of Humans and Birds, Abashiri, Hokkaido 099-3119, Japan.
Naoki TakahashiLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
Yasuhiro HasegawaDepartment of Food Science and Human Wellness, College of Agriculture, Food and Environment Science, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
Tomohito IwasakiDepartment of Food Science and Human Wellness, College of Agriculture, Food and Environment Science, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
Takafumi WatanabeLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wooden Breast is a myopathy affecting broiler chickens, characterized by hardening of the pectoral muscle, fibrosis, adipogenesis, and deteriorated meat quality. This study investigated the pathological mechanisms underlying wooden breast development, focusing on the interplay between fibrogenesis and myogenesis. Seventy-eight broiler chickens were categorized into normal, mild, and severe wooden breast groups based on the extent of fibrosis and adipogenesis in the pectoral muscle. Histological analysis revealed immature collagen fibers within muscle fascicles in severe wooden breast, indicating concurrent fibrogenesis and muscle regeneration. Immunofluorescence staining confirmed the close spatial localization of fibro-adipogenic progenitors (FAPs) and myosatellite cells in these areas, suggesting potential interaction during wooden breast pathogenesis. RNA sequencing and qPCR revealed upregulation of

Indexed as

CCN familyFAPsfibrogenesismuscle regenerationmyosatellite cellswooden breast

Identifiers

PMID42022235
PMCPMC13099151

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.