ArticleFrontiers in bioengineering and biotechnology2026
Characterization of the acetabular labrum articular surface and its translation into biomimetic graft design.
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Direct Integration of Electrospun Polycaprolactone Fibers with Polydimethylsiloxane: Influence of Elastomer Formulation on Fiber-Elastomer Adhesion.International journal of molecular sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The acetabular labrum contributes to hip joint stability and lubrication, yet its articular surface properties remain poorly characterized. Understanding and replicating these surface features is critical for developing functional labral grafts. Methods: Native bovine labra were analyzed to assess surface microstructure, lubricin distribution, local stiffness, and coefficient of friction (COF). Scanning electron microscopy, immunohistochemistry, micromechanical indentation, and pin-on-disc testing were employed, with cartilage and meniscus samples as controls. In parallel, hybrid scaffolds combining melt electrowriting (MEW) microgrids with electrospun (SES) nanofibre caps were fabricated. These constructs were structurally and mechanically evaluated by SEM, T-peel adhesion tests, tensile testing, and pin-on-disc friction measurements for comparison. Results: The bovine labrum exhibited a dense nanofibrillar surface (∼70 nm fibres), abundant lubricin, and a low COF (0.15 ± 0.03), significantly lower than cartilage or meniscus. Trypsin digestion depleted lubricin, increasing COF and reducing local stiffness. Biomimetic MEW-SES constructs demonstrated successful nanofibre capping (∼0.83 µm fibres) over MEW grids (∼16.5 µm fibres). Adhesion between layers was moderate (3-4 mN/mm) and independent of MEW spacing. Nanofibre capping enhanced tensile modulus in dense MEW grids from 2.292 to 3.261 MPa and significantly reduced COF from 0.203 to 0.117, values within the physiological range of native tissue. Conclusion: The acetabular labrum possesses unique tribological properties that can serve as a blueprint for graft design. Hybrid MEW-SES constructs replicate key structural and functional features, providing a promising approach toward engineered labral grafts. Future work should integrate biological evaluation and long-term tribological testing under physiologic conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.