Evidence map›Paper›PMID 42022068›Full record

ReviewSaudi journal of anaesthesia

Opioid stewardship program implementation in pediatric surgeries: A systematic review.

Ahmed H Mahmoud, Rayan Muawad, Plino S Ruiz, Maha M Alkharisi, Hind Z Aljedani, Manar A Alhifzi, Sarah O Alobaidy, Maysoon A Abdelhamid, Raghad S Aloubili, Norah N Almutairi and 2 more

Abstract readReview
In one paragraph

Review in Saudi journal of anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ahmed H MahmoudDepartment of Pediatric Anesthesia, King Abdullah Specialist Children Hospital, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Rayan MuawadDepartment of Pediatric Anesthesia, King Abdullah Specialist Children Hospital, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Plino S RuizDepartment of Pediatric Anesthesia, King Abdullah Specialist Children Hospital, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Maha M AlkharisiCollege of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Hind Z AljedaniCollege of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Manar A AlhifziCollege of Medicine, King Khalid University, Abha, Saudi Arabia.
Sarah O AlobaidyCollege of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Maysoon A AbdelhamidCollege of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Raghad S AloubiliCollege of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Norah N AlmutairiCollege of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Seham S AlshalahiCollege of Medicine, Majmaah University, Almajmaah, Saudi Arabia.
Abdullah AlDhuwaihyCollege of Medicine, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Postoperative opioid use in pediatric surgeries presents significant challenges due to associated risks such as dependence, oversedation, and misuse. Opioid stewardship programs (OSPs) aim to mitigate these risks by promoting appropriate opioid prescribing and multimodal pain strategies. Objectives: To evaluate the effectiveness of current OSPs and their impact on opioid prescribing practices in pediatric surgeries. Methods: We systematically searched PubMed, MEDLINE, Embase, Cochrane Library, CINAHL, and Web of Science for English language studies (2011-2024) that described opioid stewardship initiatives in pediatric surgery. Eighteen studies were included. We included randomized controlled trials, observational studies, and systematic reviews, excluding studies without a formal OSP, studies exclusively focusing on adults, and those without any specific outcomes. Data extraction and quality assessment were performed independently by multiple reviewers. Risk of bias was evaluated using Cochrane and ROBINS-I tools. Results: Eighteen studies were included with sample sizes ranging from 81 to more than 83,000 patients. The key interventions included opioid prescribing protocols, and guidelines, provider education about opioid use, and alternative pain management options to limit opioid dependence. All the studies reported reduction in opioid prescribing rates. There was reduction in discharge prescriptions from 68.4% to 10.7% after introducing consent ( Conclusion: Structured opioid stewardship interventions including protocols and guidelines, combined with targeted education and improved pain management techniques, effectively reduce opioid use while preserving adequate pain control. Future multicenter trials and studies will be required to further optimize opioid stewardship interventions and maximize patient outcomes.

Indexed as

Analgesiaanesthesiaopioidspain managementstewardship

Identifiers

PMID42022068
PMCPMC13099039

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.