ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
From cognition to daily functioning: Insights from iatrogenic cerebral amyloid angiopathy.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIatrogenic cerebral amyloid angiopathy (iCAA) is a rare form of cerebral amyloid angiopathy (CAA) caused by exposure to cadaveric dura mater grafts. Cognitive and health-related quality of life (HRQoL) outcomes in iCAA remain poorly characterized. This study explored cognitive performance and HRQoL and their associations with clinical and psychosocial factors.
methodsIn a cross-sectional study (2021-2025) at Fondazione IRCCS Istituto Neurologico Carlo Besta, probable iCAA was identified among 412 CAA patients. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) and Frontal Assessment Battery (FAB), HRQoL with Short Form-36 (SF-36) questionnaire.
resultsTwenty patients were included (40%female). Global cognition was preserved. Executive functions were associated with HRQoL general health and physical functioning. Haemorrhagic onset or recurrences were related to lower MoCA scores. Social engagement was linked to better cognitive performance and perceived health. DISCUSSION: Subtle executive dysfunction was associated with HRQoL in cognitively preserved iCAA patients, supporting the relevance of cognitive and psychosocial assessment in clinical management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.