Evidence map›Paper›PMID 42021957›Full record

ArticlePediatric discovery2026

Glucocorticoid-Induced TNFR-Related Ligand as a Biomarker for Diagnosis and Severity of Asthma in Children.

Yuehan Li, Yan Li, Jinying Xiang, Yinying Ren, Mi Zhou, Fang Deng, Zhou Fu, Fengxia Ding

Abstract read
In one paragraph

Article in Pediatric discovery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuehan LiDepartment of Respiratory Medicine Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Engineering Research Center of Stem Cell Therapy Children's Hospital of Chongqing Medical University Chongqing China.ORCID https://orcid.org/0009-0007-3350-380X
Yan LiDepartment of Respiratory Medicine Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Engineering Research Center of Stem Cell Therapy Children's Hospital of Chongqing Medical University Chongqing China.
Jinying XiangDepartment of Respiratory Medicine Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Engineering Research Center of Stem Cell Therapy Children's Hospital of Chongqing Medical University Chongqing China.
Yinying RenDepartment of Respiratory Medicine Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Engineering Research Center of Stem Cell Therapy Children's Hospital of Chongqing Medical University Chongqing China.
Mi ZhouDepartment of Respiratory Medicine Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Engineering Research Center of Stem Cell Therapy Children's Hospital of Chongqing Medical University Chongqing China.
Fang DengDepartment of Respiratory Medicine Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Engineering Research Center of Stem Cell Therapy Children's Hospital of Chongqing Medical University Chongqing China.
Zhou FuDepartment of Respiratory Medicine Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Engineering Research Center of Stem Cell Therapy Children's Hospital of Chongqing Medical University Chongqing China.
Fengxia DingDepartment of Respiratory Medicine Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Engineering Research Center of Stem Cell Therapy Children's Hospital of Chongqing Medical University Chongqing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study aimed to assess the potential of glucocorticoid-induced TNFR-related ligand (GITRL) in assessing asthma severity. Bone marrow-derived dendritic cells (BMDCs) were isolated and treated with phosphate-buffered saline (PBS) or house dust mites (HDM). Flow cytometry, immunofluorescence, and RT-qPCR results revealed that GITRL expression was increased in HDM-treated BMDCs (

Indexed as

asthmabiomarkerchildrenGITRL

Identifiers

PMID42021957
PMCPMC13098139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.