Evidence map›Paper›PMID 42021909›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2026

[Construction of an Early-stage Risk Prediction Model for Trauma-Induced Coagulopathy].

Xu Xu, Meina He, Min Shao, Xin Liu, Qi Yi, Bingyan Zhang, Ying Huang, Chaochao Tan

Abstract readEnglish Abstract
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Xu Xu() ( 410005)Department of Clinical Laboratory, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.ORCID 0009-0003-3236-8387
Meina He() ( 410005)Department of Clinical Laboratory, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.
Min Shao() ( 410005)Department of Clinical Laboratory, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.
Xin Liu() ( 410005)Department of Clinical Laboratory, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.
Qi Yi() ( 410005)Department of Clinical Laboratory, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.
Bingyan Zhang() ( 410005)Department of Clinical Laboratory, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.
Ying Huang() ( 410005)Department of Clinical Laboratory, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.
Chaochao Tan() ( 410005)Department of Clinical Laboratory, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha 410005, China.ORCID 0009-0008-4108-2598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Based on prospectively collected early clinical and laboratory data from trauma patients at admission, a risk prediction model for the early assessment of trauma-induced coagulopathy (TIC) in emergency trauma patients was constructed and validated. Methods: This study analyzed the clinical data and laboratory results of 285 emergency trauma patients admitted between January 2024 and December 2024. The patients were randomly divided into a training set ( Results: Multivariate logistic regression analysis identified head trauma, mean arterial pressure (MAP), prothrombin time (PT), and thrombin time (TT) as independent predictors of TIC, and a predictive model was developed. The AUC of the model was 0.804 (95% CI: 0.737-0.871) in the training set and 0.847 (95% CI: 0.767-0.927) in the test set. The calibration curve showed a high level of agreement between the predicted and actual probabilities. DCA indicated that the model provided significant clinical net benefit across a broad range of risk thresholds (0.2-1.0). Conclusion: This study developed and validated a TIC risk prediction model that demonstrated excellent early predictive efficacy for TIC in emergency trauma patients.

Indexed as

Blood Coagulation DisordersWounds and InjuriesAdultFemaleHumansLogistic ModelsMaleMiddle AgedPrediction AlgorithmsPrediction Methods, MachineRisk AssessmentBlood coagulation disordersLogistic modelsRisk assessmentWounds and injuries

Identifiers

PMID42021909
PMCPMC13095754

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