ArticleMedical journal of the Islamic Republic of Iran2025
NLR and Platelet Dynamics: Simple, Cost-effective Biomarkers for Stratifying Severity in Acute Pancreatitis.
Article in Medical journal of the Islamic Republic of Iran, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acute pancreatitis (AP) is characterized by pancreatic acinar cell injury and trypsin activation. Early identification of severe cases remains critical to reduce morbidity, mortality, and healthcare burden. This study aimed to evaluate the utility of accessible hematological indices-neutrophil-to-lymphocyte ratio (NLR), platelet counts (PLT), platelet-to-lymphocyte ratio (PLR), and platelet-to-white cell ratio (PWR)-as prognostic alternatives to current complex scoring systems. Methods: In this retrospective prognostic study, medical records of 150 patients (aged 18-70 years) diagnosed with AP based on the Atlanta criteria (2012) at Firouzabadi Hospital (February 2015-February 2017) were reviewed. Blood tests performed at admission, 48 hours, and 72 hours after admission were used to compute the NLR, PLR, and PWR for group comparisons. The association between these indices and prognostic scores (Ranson, Acute Physiology and Chronic Health Enquiry [APACHE-II], Glasgow, Sequential Organ Failure Assessment [SOFA], and Marshall) was assessed using independent t tests or Mann-Whitney U tests, as appropriate. To examine differences related to mortality, hematological indices were compared between survivors and nonsurvivors using the Mann‑Whitney U test or independent samples t test based on normality. Results: NLR showed significant differences with severity criteria and mortality. At 48 hours, in severe Bedside Index of Severity in Acute Pancreatitis (BISAP) cases, NLR was significantly higher (mean, 19.7 vs. 5.26; Conclusion: Significant differences between peripheral inflammatory markers across prognostic criteria suggest their potential as complementary tools for early risk stratification in AP. However, further prospective studies are warranted to confirm the prognostic utility of these indices for clinical endpoints, such as mortality and intensive care unit admission.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.