Evidence map›Paper›PMID 42021470›Full record

ArticleJournal of integrative plant biology2026

Optimized Cas-SF01 gene-editing toolbox shortens flowering timing in commercial maize inbred JING724.

Mengyuan Liu, Yao Wang, Lu Zhang, Xiang Zhang, Xiaqing Wang, Xinxiang Liu, Yue Fu, Xiaoxu Li, Ziheng Song, Ya Liu and 2 more

Abstract read
In one paragraph

Article in Journal of integrative plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mengyuan LiuBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0009-0001-8950-5616
Yao WangBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0000-0001-9923-6694
Lu ZhangBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0000-0002-2030-2394
Xiang ZhangBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0009-0001-2458-7681
Xiaqing WangBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0000-0001-5530-2311
Xinxiang LiuBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0009-0001-7721-7764
Yue FuBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0009-0007-4213-1382
Xiaoxu LiBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0009-0002-1813-5002
Ziheng SongBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0009-0008-5148-4195
Ya LiuBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0000-0001-8988-3644
Ronghuan WangBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0009-0009-5005-7439
Jiuran ZhaoBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.ORCID https://orcid.org/0000-0002-5538-7236

Funding

Beijing Postdoctoral Science Foundation 2024-zz-087
6 · The paper itself

Abstract

The gene-editing tool Cas-SF01 was optimized to maximize its efficiency in maize. The Cas-SF01-TREX2 configuration was superior in enabling high-purity gene mutations. This toolkit enabled commercial maize to flower seven days earlier without yield loss, thereby securing harvests and accelerating crop breeding.

Indexed as

CRISPR-Cas SystemsFlowersGene EditingZea maysMutationPlants, Genetically ModifiedTime FactorsCas12 familyCas‐SF01flower timemaizeZmCCT

Identifiers

PMID42021470
PMCPMC13545821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.