Trial reportCritical care (London, England)2026
Alternative net ultrafiltration rate strategies in acute kidney injury: a feasibility randomized clinical trial.
Raghavan Murugan, Victor Talisa, Chung-Chou H Chang, Nasrin Nikravangolsefid, Waryaam Singh, Brad W Butcher, Ali Al-Khafaji, Scott Gunn, Firas Abdulmajeed, Phillip Lamberty and 4 more
Abstract readRandomized Controlled TrialMulticenter Study
In one paragraphTrial report in Critical care (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Raghavan MuruganThe Program for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America. muruganr@upmc.edu.ORCID http://orcid.org/0000-0002-6823-6365 Victor TalisaThe Center for Research, Investigation, and Systems Modeling of Acute Illness (CRISMA), Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.ORCID http://orcid.org/0000-0001-5246-0349 Chung-Chou H ChangThe Center for Research, Investigation, and Systems Modeling of Acute Illness (CRISMA), Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.ORCID http://orcid.org/0000-0003-3665-6928 Nasrin NikravangolsefidDivision of Nephrology and Hypertension, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Waryaam SinghDivision of Nephrology and Hypertension, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Ali Al-KhafajiDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
Scott GunnDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
Firas AbdulmajeedDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
Phillip LambertyDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
David HuangThe Center for Research, Investigation, and Systems Modeling of Acute Illness (CRISMA), Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.ORCID http://orcid.org/0000-0001-7649-1633 Paul M PalevskyThe Program for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.ORCID http://orcid.org/0000-0002-7334-5400 Kianoush KashaniDivision of Nephrology and Hypertension, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID http://orcid.org/0000-0003-2184-3683 Restrictive versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury (RELIEVE-AKI) Study Investigators
Funding
REstrictive versus LIberal rate of Extracorporeal Volume removal Evaluation in Acute Kidney Injury (RELIEVE-AKI)R01DK128100 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KASHANI, KIANOUSH B, MURUGAN, RAGHAVAN · 2021 to 2023
$965kNIDDK NIH HHS R01 DK128100NIDDK NIH HHS R01DK128100
6 · The paper itselfAbstract
Observational studies link high net ultrafiltration (UF
Indexed as
Acute Kidney InjuryContinuous Renal Replacement TherapyAgedFeasibility StudiesFemaleHumansIntensive Care UnitsMaleMiddle AgedUltrafiltrationAcute kidney injuryContinuous kidney replacement therapyFeasibilityNet fluid removalNet ultrafiltrationUltrafiltration rate
Identifiers
PMID42021350
PMCPMC13141483
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
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