Evidence map›Paper›PMID 42021251›Full record

ArticleBMC musculoskeletal disorders2026

Graft position versus material in posterior atlantoaxial fusion: establishing a clinical decision hierarchy.

Hua Liu, Tao Zhang, Tao Zhang, Hua Liu, Songkai Li

Abstract readComparative Study
In one paragraph

Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Hua Liu *Department of Spinal Surgery, The 940th Hospital of the Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, 730050, Gansu, China.ORCID http://orcid.org/0009-0000-4516-826X
Tao Zhang *Department of Spinal Surgery, The 940th Hospital of the Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, 730050, Gansu, China.ORCID http://orcid.org/0000-0001-7666-4696
Tao Zhang *Department of Spinal Surgery, The 940th Hospital of the Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, 730050, Gansu, China.ORCID http://orcid.org/0000-0003-2308-094X
Hua Liu *Department of Spinal Surgery, The 940th Hospital of the Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, 730050, Gansu, China.ORCID http://orcid.org/0000-0003-0593-9001
Songkai LiDepartment of Spinal Surgery, The 940th Hospital of the Joint Logistic Support Force of Chinese People's Liberation Army, Lanzhou, 730050, Gansu, China. lisongkai1204@qq.com.ORCID http://orcid.org/0000-0002-9200-2390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal bone grafting strategy for posterior atlantoaxial fusion remains controversial, with the interplay between graft position (interlaminar vs. intra-articular) and material (allograft vs. autograft) poorly understood. We aimed to evaluate their interactive effects on clinical and radiographic outcomes.

methodsIn this single-center retrospective cohort study, 52 patients with atlantoaxial instability were categorized into three groups: Group A (n = 18, interlaminar allograft), Group B (n = 19, intra-articular allograft), and Group C (n = 15, intra-articular autograft). Primary outcomes included the Japanese Orthopaedic Association (JOA) score, Neck Disability Index (NDI), Visual Analog Scale (VAS) for neck pain, fusion time, and lateral mass joint space height. Analysis of covariance (ANCOVA) was used to compare final clinical scores, adjusting for baseline values.

resultsANCOVA revealed a significant main effect of group on final JOA (P < 0.001) and NDI (P = 0.003). Both intra-articular groups (B and C) demonstrated significantly better functional outcomes than the interlaminar group (A), with no difference between B and C. VAS improvement was comparable across groups (P = 0.925). Fusion time was shortest in Group C (6.34 ± 0.97 months) versus both Group A (8.83 ± 1.76, P < 0.001) and Group B (8.22 ± 1.27, P = 0.001). Intra-articular allograft achieved greater immediate joint distraction, while autograft better maintained joint height long-term.

conclusionsIn this retrospective cohort study, our findings identify a clear clinical decision hierarchy for posterior atlantoaxial fusion: graft position is the primary determinant of functional outcomes, with intra-articular grafting associated with superior neurological and functional recovery compared to interlaminar grafting. Within the intra-articular space, a material-specific clinical trade-off exists: autograft facilitates faster fusion and better joint height maintenance, while allograft provides comparable mid-term functional outcomes without harvest-site morbidity. These findings suggest that surgical strategy should prioritize intra-articular graft placement when anatomically feasible, with graft material selection individualized to patient factors and surgical priorities.

Indexed as

Atlanto-Axial JointBone TransplantationClinical Decision-MakingJoint InstabilitySpinal FusionAdultAllograftsAutograftsFemaleHumansMaleMiddle AgedRetrospective StudiesTransplantation, AutologousTreatment OutcomeYoung AdultAllograftAtlantoaxial instabilityAutograftBone graftLateral mass jointPosterior fusion

Identifiers

PMID42021251
PMCPMC13238073

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.