ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2026
Improvement in Image Quality and Efficiency of Non-contrast Thoracic MR Angiography: Comparison of a Highly Accelerated Dixon-based Technique with the Conventional Fat-suppressed Technique.
Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo compare the image quality and acquisition time of thoracic great vessels using a novel, 3D isotropic non-contrast-enhanced MR angiography that combines respiratory compensation, electrocardiogram-triggering, compressed sensing, and Dixon water-fat separation at 3T (CS-MRA) to a conventional MRA employing parallel imaging and spectral attenuated inversion recovery (cMRA).
methodsThis study included 20 healthy volunteers and 19 patients with thoracic vascular diseases. All scans were performed on a 3T MRI scanner using a T2-prepared 3D fast low angle shot (FLASH) sequence. Visual image quality of thoracic great vessels was assessed using a 4-point scale. Quantitative parameters including SNR, contrast-to-noise ratio (CNR), contrast ratio (CR), and coefficient of variation (CV) were evaluated. Aortic diameters were measured, and reproducibility was assessed using Bland-Altman analysis and the intraclass correlation coefficient (ICC). Image acquisition times were also compared.
resultsVisual assessment demonstrated significantly higher scores with CS-MRA compared to cMRA across all evaluated thoracic vessels in both volunteers and patients (median score: 3 vs. 2, P < 0.05). Quantitative analysis showed that CS-MRA yielded significantly higher SNR, CNR, and CR (P < 0.05 for all), along with better signal homogeneity (lower CV). CS-MRA showed excellent intra- and inter-observer agreement for aortic diameter measurements, with ICCs ≥ 0.91 in volunteers and ≥ 0.95 in patients. CS-MRA also achieved significantly shorter acquisition times (volunteers: 5.3 ± 1.4 min vs. 6.0 ± 1.7 min, P < 0.01; patients: 5.1 [4.6-6.3] min vs. 6.9 [5.0-9.6] min, P < 0.01).
conclusionCS-MRA provides superior image quality, comparable measurement reproducibility, and significantly reduced acquisition times compared to cMRA. These findings support the clinical utility of CS-MRA as an efficient and reliable non-contrast technique for thoracic vascular evaluation.
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