Evidence map›Paper›PMID 42020908›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Intravitreal Injections in Mouse Models of Eye Disease.

Annie L Miller, Yashvi Bhatt, Livia S Carvalho

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Annie L MillerCentre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, WA, Australia. annie.miller@lei.org.au.
Yashvi BhattCentre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, WA, Australia.
Livia S CarvalhoCentre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, WA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravitreal injections are a commonly used technique in the treatment of some vitreoretinal diseases. In clinical situations, intravitreal injections are often used to deliver drugs that treat diseases such as age-related macular degeneration, retinal vein occlusion, and uveitis. Many preclinical studies in animals such as mice utilize intravitreal injections to test neuroprotective treatments and gene therapies before clinical use can be indicated. Herein, we describe our method and favorable practices for intravitreal injection into the eye of both preweaned and adult mice.

Indexed as

Eye DiseasesIntravitreal InjectionsAnimalsDisease Models, AnimalMiceDrug deliveryIntravitreal injectionMouse modelsTransscleralVitreoretinal disease

Identifiers

PMID42020908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.