ArticleNature2026
Focal white matter lesions drive grey matter inflammation and synapse loss.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Riluzole shifts glial responses to protect synapses and memory in Aβ oligomer-treated rats.Journal of neuroinflammation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
Omar de FariaCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-7919-9555
Stavros Vagionitis *Cambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-9501-0695
Andrea Lopez-Lopez *Cambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Michael Perry *Cambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Joseph Jo Yin WongCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Leslie Rodríguez-KirbyLaboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Bastien HervéLaboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-2610-8365
Balazs Viktor VargaCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-4005-1203
Eneritz AgirreLaboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-5012-0305
Sabrina GhoshCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Sebastian TimmlerCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-9258-2965
Mert YucelCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Andrew T SetleyElectrical Engineering Division, University of Cambridge Department of Engineering, Cambridge, UK.ORCID http://orcid.org/0009-0004-9746-3091
Kimberley Anne EvansCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Tanja Mist BirgisdóttirDepartment of Physiology, BioMedical Center, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Sindri GíslasonDepartment of Physiology, BioMedical Center, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Yan Ting NgCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0009-0006-4183-1224
Courtney KremlerCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Helene O B GautierCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Yasmine KamenCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-1867-7397
Helena PivonkovaCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Katrin VolbrachtCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-6585-263X
Felix HildebrandCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Christian A CepedaCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Javier Rueda-CarrascoUK Dementia Research Institute, University College London, London, UK.ORCID http://orcid.org/0000-0002-9280-6612
Soyon HongUK Dementia Research Institute, University College London, London, UK.ORCID http://orcid.org/0000-0002-5744-4871
George MalliarasElectrical Engineering Division, University of Cambridge Department of Engineering, Cambridge, UK.ORCID http://orcid.org/0000-0002-4582-8501
Sabine DietmannInstitute for Informatics, Washington University School of Medicine, St Louis, MO, USA.
Gonçalo Castelo-BrancoLaboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-2247-9393
Ragnhildur Thóra KáradóttirCambridge Centre for Myelin Repair, Cambridge Stem Cell Institute & Department of Veterinary Medicine, University of Cambridge, Cambridge, UK. rk385@cam.ac.uk.ORCID http://orcid.org/0000-0001-9675-2722
Funding
No grant is acknowledged in the PubMed record.
Abstract
Focal white matter lesions occur in most neurodegenerative disorders
Indexed as
Gray MatterInflammationNeuroinflammatory DiseasesSynapsesWhite MatterAnimalsFemaleMaleMiceMicrogliaMyelin SheathNeurodegenerative DiseasesRatsRegeneration
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.