Evidence map›Paper›PMID 42020576›Full record

ReviewJournal of muscle research and cell motility2026

Smooth muscle contractile cytoskeleton in health and disease.

Glenn Carrington, Malika Zahedi, Michelle Peckham

Abstract readReview
In one paragraph

Review in Journal of muscle research and cell motility, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Glenn CarringtonSchool of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
Malika ZahediSchool of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
Michelle PeckhamSchool of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK. m.peckham@leeds.ac.uk.

Funding

Wellcome TrustWellcome Trust 223125/Z/21/Z
6 · The paper itself

Abstract

Smooth muscle cells are widespread in the human body, found in a range of tissues from the vasculature to the gut, airways, bladder and so on. They can be found as isolated cells or organised into syncytia (groups of cells). The organisation of the contractile cytoskeleton (smooth muscle actin and myosin filaments) is less well understood than that of striated (cardiac and skeletal) muscle. This review aims to explore what is known, the potential effects of mutations in smooth muscle actin, myosin and tropomyosin and how they lead to disease, and to highlight what we have still to learn about the smooth muscle contractile cytoskeleton.

Indexed as

CytoskeletonMuscle ContractionMuscle, SmoothActinsAnimalsHumansMyosinsActinsMyosinsActinCaldesmonCalponinCytoskeletonMyosinSmooth Muscle

Identifiers

PMID42020576
PMCPMC13102872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.