Evidence map›Paper›PMID 42020453›Full record

ArticleScientific data2026

The University of Texas Southwestern Glioma Dataset - MRI, Molecular Markers and Segmentations.

Divya D Reddy, Niloufar Saadat, James M Holcomb, Benjamin C Wagner, Nghi C Truong, Jason Bowerman, Kimmo J Hatanpaa, Toral R Patel, Marco C Pinho, Fang Yu and 5 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Divya D ReddyAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID http://orcid.org/0000-0001-5899-0981
Niloufar SaadatAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
James M HolcombAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Benjamin C WagnerAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Nghi C TruongAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID http://orcid.org/0000-0002-2195-3850
Jason BowermanAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kimmo J HatanpaaDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Toral R PatelDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Marco C PinhoAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Fang YuAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kuan ZhangAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Sadeem LodhiAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Ananth J MadhuranthakamDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Chandan Ganesh Bangalore YoganandaAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Joseph A MaldjianAdvanced Neuroscience Imaging Research lab, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. joseph.maldjian@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-6384-1072

Funding

Virtual Biopsy with Tissue-level Accuracy in GliomaR01CA260705 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MALDJIAN, JOSEPH A · 2021 to 2025
$3.1M
U.S. Department of Health & Human Services | NIH | Center for Information Technology (Center for Information Technology, National Institutes of Health) R01CA260705U.S. Department of Health & Human Services | NIH | NCI | Division of Cancer Epidemiology and Genetics, National Cancer Institute (National Cancer Institute Division of Cancer Epidemiology and Genetics) R01CA260705
6 · The paper itself

Abstract

Gliomas are the most common type of primary brain tumors. Their management options and outcomes depend significantly on the underlying molecular-marker profile. Traditionally, molecular markers are determined through pathological testing on a tissue specimen acquired through biopsy. Several Magnetic Resonance Imaging (MRI) based Deep Learning (DL) methods offer a promising, non-invasive approach to predict these markers. However, they often require high-quality, well-annotated datasets. To support this need, we present a well-curated brain tumor dataset developed at The University of Texas Southwestern (UTSW) Medical Center. This dataset includes multi-contrast-MRI, demographics, molecular-markers, and multi-label tumor segmentations for 625 patients treated at UTSW between 2006 and 2023. Each patient record contains four MRI contrasts: pre-contrast-T1w, post-contrast-T1w, T2w, and T2-weighted fluid-attenuated inversion recovery (T2w-FLAIR) images. The dataset also provides comprehensive genetic information, including IDH mutation-status, 1p19q co-deletion, MGMT promoter methylation, tumor-type, and tumor-grade. This dataset offers a valuable resource for exploring the relationship between MRI characteristics and tumor genetics. It also serves as a robust benchmark for developing and validating DL models for various downstream tasks.

Indexed as

Biomarkers, TumorBrain NeoplasmsGliomaMagnetic Resonance ImagingDeep LearningHumansMutationTexasBiomarkers, Tumor

Identifiers

PMID42020453
PMCPMC13287574

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.