ReviewCritical care science2026
The clinical significance of intracranial pressure waveform analysis in brain-injured patients.
Review in Critical care science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intracranial pressure monitoring is a cornerstone in neurocritical care, particularly for patients with acute brain injury. Historically, management has focused on absolute intracranial pressure thresholds, but a paradigm shift is underway towards dynamic assessment of intracranial compliance through intracranial pressure waveform analysis. This short review synthesizes recent advancements in understanding intracranial compliance pathophysiology, explores sophisticated invasive and non-invasive monitoring techniques, and discusses their evolving clinical implications. We highlighted how parameters derived from intracranial pressure waveforms, such as the P2/P1 ratio, pulse shape index, and mean pulse amplitude, provide granular insights into the brain compensatory reserve and cerebrovascular autoregulation. Integrating these new pathophysiological insights with advanced monitoring tools holds immense potential to refine clinical decision-making, enabling more proactive, personalized interventions to improve outcomes for patients with acute brain injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.